نتایج جستجو برای: solid lipid nanoparticles sln
تعداد نتایج: 449133 فیلتر نتایج به سال:
In this study, resveratrol-loaded solid lipid nanoparticles (Res-SLNs) were successfully designed to treat MDA-MB-231 cells. The Res-SLNs were prepared using emulsification and low-temperature solidification method. The Res-SLNs were spherical, with small size, negative charge, and narrow size distribution. Compared with free resveratrol, the Res-SLNs displayed a superior ability in inhibiting ...
Introduction & Objective: Cryptosporidiosis caused by Cryptosporidium, which is a protozoan parasite, has a worldwide distribution. The infection is through fecal-oral route, direct or indirect contact, food or water. The treatment of cryptosporidiosis is difficult and the anti-parasitic agents are not effective. The purpose of this study was encapsulation of nitazoxanide in solid lipid nano-pa...
2001;409:66–9. 10. Cui Y, Lieber CM. Functional nanoscale electronic devices assembled using silicon nanowire building blocks. Science 2001;291:851–3. 11. Kim P, Lieber CM. Nanotube nanotweezers. Science 1999;286:2148–50. 12. Cobden DH. Molecular electronics. Nanowires begin to shine. Nature 2001;409:32–3. 13. Mehnert W, Mader K. Solid lipid nanoparticles: production, characterization and appli...
Solid lipid nanoparticles have been increasingly utilised for improving oral bioavailability of drugs. Simvastatin is biopharmaceutical class 2 drug with poor oral bioavailability of 5%. In the present study, simvastatin solid lipid nanoparticles were successfully prepared by hot melt emulsification process and optimised with respect to surfactant and lipid concentration, and drug loading. The ...
Aim: The aim of the present study was to design and evaluate solid lipid nanoparticles Asenapine maleate (<2% bioavailability) enhance its oral bioavailability surface modification for brain targeting.
 Methods: A modified solvent injection method used produce loaded nanoparticles. RSM 3-factor, 3-level Box-Behnken applied effect three independent variables, concentrations (A), drug (B)...
Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics. The ability to incorporate drugs into nanoparticles offers a new prototype in drug delivery thus realizing the dual goal of both controlled release and site-specific drug delivery. Drug deliv...
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