Interstitium contains a matrix of fibrous molecules that creates considerable resistance to water and solutes in series with the microvessel wall. On the basis of our preliminary studies, by using laser-scanning confocal microscopy and a theoretical model for interstitial transport, we determined both microvessel solute permeability (P) and solute tissue diffusion coefficient (D) of alpha-lacta...

Perfusion studies were performed in healthy volunteers to test the hypothesis that net fluid secretion induced by fatty acids is accompanied by parallel reduction in solute transport. Ricinoleic acid provoked a marked net secretion of fluid and concomitantly inhibited the absorption of all solutes tested; these included glucose, xylose, L-leucine, L-lysine, Folic acid, and 2-mono-olein. Oleic a...

Perfusion studies were performed in healthy volunteers to test the hypothesis that net fluid secretion induced by fatty acids is accompanied by parallel reduction in solute transport. Ricinoleic acid provoked a marked net secretion of fluid and concomitantly inhibited the absorption of all solutes tested; these included glucose, xylose, L-leucine, L-lysine, folic acid, and 2-mono-olein. Oleic a...

Noncontact manipulation of nano/micromaterials presents a great challenge in fields ranging from biotechnology to nanotechnology. In this study we developed a new strategy for the manipulation of molecules and cells based on diffusiophoresis driven by a concentration gradient of a polymer solute. By using laser focusing in a microfluidic device, we created a sharp concentration gradient of poly...

Hamad, F. and Mansoori, G.A., 1993. Theory of infinite dilution chemical potential. Fluid Phase Equilibria, 85: 141151. Exact expressions for the infinite dilution chemical potential in terms of the pair correlation function are derived. Appropriate approximations are introduced in these expressions to derive simple equations for the infinite dilution chemical potential in terms of molecular si...

We construct a mesoscale model of colloidal suspensions that contain solutes reversibly adsorbing onto the colloidal particle surfaces. The present model describes the coupled dynamics of the colloidal particles, the host fluid, and the solutes through the Newton-Euler equations of motion, the hydrodynamic equations, and the advection-diffusion equation, respectively. The solute adsorption is m...

Selective extraction of a protein from a mixture can be accomplished using an adsorptive membrane and low displacement recuperative parametric pumping. Low displacement recuperative parametric pumping can lead to the preferential transport of an adsorbing solute and the rejection of nonadsorbing solutes by the adsorptive membrane. Using a protein mixture consisting of lysozyme and myoglobin, we...

Physiologists have devised many models for interpreting water and solute exchange data in whole organs, but the models have typically neglected key aspects of the underlying physiology to present the simplest possible model for a given experimental situation. We have developed a physiologically realistic model of microcirculatory water and solute exchange and applied it to diverse observations ...

A cylindrical treatment of the configuration of small molecules in solution has been proposed. Cylindrical dimensions were obtained from Fisher-Hirschfelder molecular models, and these dimensions were used in an analysis of three sets of reflection coefficient values from the literature. The correlation between solute dimensions and the reflection coefficient was subjected to both statistical a...