Objective: Buccal drug delivery is the most suited route for local as well systemic of drugs. Cilnidipine an L/N type dihydropyridine 4th generation calcium channel blocker (CCB), which decreases hypertension by blocking N-type to attenuate vascular sympathetic neurotransmission. It has high first-pass metabolism leading low bioavailability. Hence present research work was undertaken formulate ...

Antioxidant and antimicrobial free-standing films composed of nanofibrillated cellulose (NFC) a polyphenolic-rich extract, viz. mango leaf extract (MLE), were produced via supercritical solvent impregnation (SSI) conventional casting film-processing methodologies. The CO2-assisted NFC with MLE created robust thermal stability up to 250 °C, good mechanical performance (Young's modulus > 4.7 GPa)...

BACKGROUND Although botulinum toxin A is frequently used to augment serial casting in the treatment of soft-tissue contractures in children with cerebral palsy, its effectiveness for this purpose has not been evaluated. The purpose of the present study was to determine whether botulinum toxin A injection increases the efficacy of serial casting. METHODS A prospective, randomized trial was und...

The solidification of metals continues to be a phenomenon of great interest to physicists, metallurgists, casting engineers and software developers. It is a non-linear transient phenomenon, posing a challenge in terms of modelling and analysis. During the solidification of a casting in a mould, the heat-transfer between the casting and the mould plays a vital role. This paper attempts to study ...

In this study, porous natural rubber (NR) films loaded with silver nanoparticles (AgNPs) were prepared by the solvent casting method. The structure of NR was formed hydrophilic substances such as glycerol, pectin or carrageenan. film properties including morphology, mechanical test, hydrophilicity evaluation, water absorption, release and antibacterial activity determined. From results, morphol...

A stumbling point for many learning to fly fish is being able to fly cast well enough to ‘present’ a fly to a feeding fish. Even among more skilled fly fishers, learning to fly cast better is often a bottleneck towards advancement in the sport. Fly casting instruction today relies on the visual inspection of the fly casting stroke and the resulting ‘loop’ of fly line. These qualitative visual c...

This paper describes a method to generate Delaunay tetrahedral meshes directly from regular volume data by vertex insertion driven by an error criterion. By adapting the mesh to the input data, the method produces meshes suitable for fast and precise volume ray-casting. A partitioning method that splits the mesh into homogeneous sub-meshes is also presented. Such mesh segmentation strategy turn...

There is a growing need for custom visualization applications to deal with the rising amounts of volume data to be analyzed in fields like medicine, seismology, and meteorology. Visual programming techniques have been used in visualization and other fields to analyze and visualize data in an intuitive manner. However, this additional step of abstraction often results in a performance penalty du...

In this study, the composite films of polyvinyl alcohol (PVA) and graphene oxide (GO) that referred as PVA/GO composites were prepared with a solution casting technique to be used filtration membrane. was by mixing PVA powder, GO dispersion aqueous solvent, then subjected hydrothermal process. The cast on glass substrate, dried overnight so solvent evaporated removed from substrate. characteriz...