نتایج جستجو برای: sonority sequencing principle

تعداد نتایج: 279072  

2017
Joseph Larkin Robert Y Henley Vivek Jadhav Jonas Korlach Meni Wanunu

Compared with conventional methods, single-molecule real-time (SMRT) DNA sequencing exhibits longer read lengths than conventional methods, less GC bias, and the ability to read DNA base modifications. However, reading DNA sequence from sub-nanogram quantities is impractical owing to inefficient delivery of DNA molecules into the confines of zero-mode waveguides-zeptolitre optical cavities in w...

2017
Laura S Kremer Daniel M Bader Christian Mertes Robert Kopajtich Garwin Pichler Arcangela Iuso Tobias B Haack Elisabeth Graf Thomas Schwarzmayr Caterina Terrile Eliška Koňaříková Birgit Repp Gabi Kastenmüller Jerzy Adamski Peter Lichtner Christoph Leonhardt Benoit Funalot Alice Donati Valeria Tiranti Anne Lombes Claude Jardel Dieter Gläser Robert W Taylor Daniele Ghezzi Johannes A Mayr Agnes Rötig Peter Freisinger Felix Distelmaier Tim M Strom Thomas Meitinger Julien Gagneur Holger Prokisch

Across a variety of Mendelian disorders, ∼50-75% of patients do not receive a genetic diagnosis by exome sequencing indicating disease-causing variants in non-coding regions. Although genome sequencing in principle reveals all genetic variants, their sizeable number and poorer annotation make prioritization challenging. Here, we demonstrate the power of transcriptome sequencing to molecularly d...

1997
Katy Carlson

(1997) has led to a similar analysis of Nakanai reduplication in the context of his dissertation 1 on languages with multiple reduplication patterns.

Journal: :PLoS ONE 2008
Julie Doostzadeh Shadi Shokralla Farnaz Absalan Roxana Jalili Sharareh Mohandessi James W. Langston Ronald W. Davis Mostafa Ronaghi Baback Gharizadeh

Pyrosequencing is a DNA sequencing method based on the principle of sequencing-by-synthesis and pyrophosphate detection through a series of enzymatic reactions. This bioluminometric, real-time DNA sequencing technique offers unique applications that are cost-effective and user-friendly. In this study, we have combined a number of methods to develop an accurate, robust and cost efficient method ...

Journal: :medical journal of islamic republic of iran 0
a kazemi immunology and parasitology department , school of medicine, tabriz university of medical sciences, tabriz, i.r. iran g.d robson d.w denning

background and objectives: annexin is the common name for genes and proteins that were identified as calcium-dependent phospholipid-binding proteins. recently a more complex set of functions has been recognized for this superfamily of proteins including in vesicle trafficking, cell division, apoptosis, calcium signalling, mineralization, crystal nucleation inside the extracellular organelles-ma...

Journal: :iranian journal of public health 0
shaghayegh sabri manouchehr keyhani mohammad taghi akbari

background: previous studies have shown that leukemogenic chromosomal translocations, including fusions between break point cluster region (bcr) and abelson (abl) are present in the peripheral blood of healthy individuals. the aim of this study was to gain insights into the genetic alterations other than bcr-abl translocation in molecular level, which cause chronic myeloid leukemia (cml). metho...

Journal: :modares journal of medical sciences: pathobiology 2012
elham ahmadi hooreih soleimanjahi majid sadegizadeh ali teimoori

objective: group a rotaviruses (garv) are responsible for the vast majority of severe diarrhea worldwide that kills an estimated 600,000-870,000 children annually. since infantile gastroenteritis is a main health problem, therefore diagnosis and treatment of this disease is crucial. gene rearrangements have been detected in vitro during serial passages of the virus at a high multiplicity of inf...

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