With the rapid development of industry and agriculture and associated pollution, the cyanobacterial blooms in Lake Taihu have become a major threat to aquatic wildlife and human health. In this study, the ecotoxicological effects of cyanobacterial blooms on cage-cultured carp (Cyprinus carpio L.) in Meiliang Bay of Lake Taihu were investigated. Microcystins (MCs), major cyanobacterial toxins, h...

BACKGROUND Transgenic mice with constitutive myocardium-targeted expression of a peptide inhibitor of the ss-adrenergic receptor kinase (ssARKct) have increased in vivo cardiac function and enhanced ss-adrenergic receptor (ssAR) responsiveness. METHODS AND RESULTS In the present study, we created transgenic mice with myocardium-targeted ssARKct transgene expression under control of the CARP (...

Beyond their sequences, little is known regarding MHC class I presentation and regulation by IFN in bony fish. In this work, the class I locus (Ctid-UBA) was isolated from a grass carp fosmid library, and its polymorphisms and tissue expression were investigated. The Ctid-UBA and Ctid-beta2-microglobulin genes then were expressed and refolded, and tetramer techniques were used to identify the C...

Plant extracts have a long history to be used in folk medicine. Cassia alata extracts are known to exert antibacterial activity but details on compounds and mechanism of action remain poorly explored. We purified and concentrated the aqueous leaf extract of C. alata by reverse phase-solid phase extraction and screened the resulting CaRP extract for antimicrobial activity. CaRP extract exhibited...

Background In rheumatoid arthritis (RA) many patients harbor autoantibodies against post translationally modified proteins (anti-modified protein antibodies (AMPA)): anti-citrullinated (ACPA), anti-carbamylated (anti-CarP) and anti-acetylated (AAPA). All three AMPA have been described to be associated with an increase in radiographic joint damage ACPA also a lower chance of obtaining sustained ...

A saw-toothed chessboard, or STC for short, is a kind of chessboard whose boundary forms two staircases from left down to right without any hole inside it. A rook at square (i, j) can dominate the squares in row i and in column j . The rook problem of an STC is to determine the minimum number of rooks that can dominate all squares of the STC. In this paper, we model an STC by two particular gra...

some biochemical characteristics of common carp (cyprinus carpio) and silver carp (hypophtalmichthys moltrix) surimi prepared by a conventional washing method and protein isolated using alkaline-acid-aided processes were investigated. solubility of protein in silver carp and common carp were found to be highest by using the conventional washing method. decreases in myoglobin and lipid contents ...

The interactions of Flavobacterium columnare isolates of different virulence with the gills of carp (Cyprinus carpio L.) and rainbow trout (Oncorhynchus mykiss Walbaum) were investigated. Both fish species were exposed to different high (HV) or low virulence (LV) isolates and sacrificed at seven predetermined times post-challenge. Histopathological and ultrastructural examination of carp and ra...

BACKGROUND Body color and coloration patterns are important phenotypic traits to maintain survival and reproduction activities. The Oujiang color varieties of common carp (Cyprinus carpio var. color), with a narrow distribution in Zhejiang Province of China and a history of aquaculture for over 1,200 years, consistently exhibit a variety of body color patterns. The molecular mechanism underlyin...

Pizza being the most popular food worldwide, quality and sensory appeal are important considerations during its modification effort. This study was aimed to evaluate the quality of pizza made using two different sources of proteins, chickpea (Cicer arietinum) flour and dried carp fish powder (Cyprinus carpio). Analysis indicated nutrients richness specificity of chickpea flour (higher fiber, en...