BACKGROUND Curcuma extract exerts a myorelaxant effect on the mouse intestine. In view of a possible use of curcuma extract in motor functional disorders of the gastrointestinal tract, a safety profile study has been carried out in the mouse. METHODS Thirty mice were used to study the in vitro effect of curcuma on gallbladder, bladder, aorta and trachea smooth muscular layers and hearth inotr...

reticulorumen hypomotility leads to the impaired physiologic functions of the digestive tract. prokinetic action of ginger has been demonstrated in the laboratory animals and human. the aim of this study was to evaluate the effect of hydroalcoholic extract of ginger on contraction and motility of reticulum and rumen of ruminants. collected samples of reticulum and rumen from eight sheep were in...

isovanillin and isoacetovanillon are two components found in p. spinosa decne.exboiss extract with no previously reported effect on ileum contractions. spasmolytic effect of isovanillin and isoacetovanillon were examined on response to electrical field stimulation (efs), acetylcholine (ach) and 5-ht in strips of rat ileum. longitudinal ileum strips were set up in an organ bath containing oxygen...

OBJECTIVE To study the possible effects of methanolic extract of fruits of Tamarindus indica on rabbit's jejunum preparations. MATERIALS AND METHODS The study was carried out on rabbit's jejunum preparations. Methanolic extract of fruits of T. indica was applied in different doses. Potassium chloride (KCl 80 mM)-induced contractions were relaxed by the extract. For determination of possible m...

Department of Animal Biology, P.O.Box 67 Dschang, University of Dschang, Cameroon Institut of Pharmacology and Toxicology, Technical University of Munich, Biedersteiner strasser 29, 80802 munich, Germany Department of Animal Biology and Physiology, P.O.Box 24157 Douala, University of Douala, Cameroon Department of Animal Biology and Physiology, P.O.Box 812 Yaounde, University of Yaounde I, Came...

Cymbopogon martinii (Cm.Cr) is traditionally used in south Asian communities for the management of multiple ailments including gastrointestinal, respiratory and vascular disorders and the present study was undertaken to validate these folkloric uses. The application of a methanol extract of the plant (Cm.Cr) to isolated rabbit jejunum preparation exhibited relaxation through decrease in magnitu...

By P. J. WARD, L.R.C.P.I., L.M., L.R.C.S.I., D.P.H. Bessbrook, Newry, Co. Down THE progressive arterial deterioration which accompanies ageing, may manifest itself in a variety of symptoms-all causing distress to the patient and increased problems for the physician. Elderly patients with advanced arteriosclerosis usually present one or more predominant signs or symptoms against a background of ...