Sixty-three patients, who had had a partial gastrectomy 15--27 years previously, were examined by endoscopy and multiple mucosal biopsies. No patient had a completely normal gastric mucosa; they showed varying degrees of gastritis, intestinal metaplasia, and dysplasia: 21% had significant dysplasia, and these are regarded as an 'at-risk' group requiring frequent follow-up examinations. One pati...

Infiltrating ductal carcinoma arising in a fibroadenoma is a rare incidental finding. Incidence is 0.0020.0125%. Women having proliferative disease without atypia have a twofold elevation in their risk for subsequent invasive breast cancer. We here present a case report in a 38 year female having fibroadenoma, intraductal papilloma and fibocystic disease of breast who subsequently developed inv...

BACKGROUND: Coexistence of cancer and tuberculosis in axillary lymph nodes is rare. Only seven cases have been reported in the literature. CASE REPORT: We report here a case of infiltrating ductal carcinoma breast metastasizing to the axillary lymph node along with tubercular granuloma in the same lymph node without primary mammary or pulmonary tuberculosis. CONCLUSION: Primary tuberculosis coe...

CORTACTIN is an actin-binding protein critically involved in cellular migration and invasion. Here, we investigated the role of CORTACTIN in the pathophysiology of orohypopharynx carcinoma - one of the major subtypes of head and neck cancer. To this end, we analyzed CORTACTIN expression in tumor tissues from 89 orohypopharynx carcinoma patients in relation to clinical parameters. We found that ...

Background: Among the parameters that have a prognostic and/or predictive significance to therapeutic response, in case of breast carcinoma, study tumor-infiltrating lymphocytes carcinomas is emerging. The present aimed access clinicopathological profiles patients with primary carcinoma. Materials and Methods: Information was collected from archive Department Pathology, about invasive cancers d...

Carol Edwards, a 39 year-old premenopausal woman, had a screening mammogram which revealed an abnormality in the right breast. She had no palpable masses on breast exam. A mammographically localized surgical biopsy was done and revealed a small (0.9 cm) grade III infiltrating ductal carcinoma with some associated ductal carcinoma-in-situ (DCIS). The surgical margins were not clear (cancer cells...

A case in which an infiltrating mucinous carcinoma developed within a suprasphincteric fistula-in-ano is presented. The diagnosis was suspected on biopsy and confirmed by repeat biopsy. The clinical and histological features of this case establish with certainty that the carcinoma arose within the fistula and was not a secondary manifestation of the tumour. It is suggested that this rare compli...

OBJECTIVE The goal of this study was to detect the intertumoral heterogeneity of CT10, CT45 and GAGE7 expression and further to analyze their prognostic value. METHODS The intertumoral heterogeneity of three cancer/testis antigens was examined by immunohistochemistry using 120 samples from patients with infiltrating ductal breast carcinoma. The expression patterns were classified and correlat...

A 63-year-old female smoker was evaluated for lump over the right breast, fine needle aspiration cytology of which showed infiltrating ductal carcinoma. Investigations also revealed the presence of left upper lobe mass lesion, the biopsy of which suggested small cell carcinoma. The existence of two malignancies having different histopathologies at anatomically distinct sites suggests the diagno...

Here we present a series of infiltrative ductal carcinoma breast cases (infiltrative ductal carcinoma with central necrosis) so closely mimicking 'DCIS with central comedo necrosis' that on initial morphological analysis these foci of tumors were labeled as DCIS (high grade, comedo). However on further histological work up and by using immunohistochemistry (IHC) for myoepithelial markers it was...