[Purpose] To investigate the influence of the level of spinal cord injury on the thermic effect of food intake (TEF) in persons with thoracic spinal cord injury. [Subjects and Methods] Seven male subjects with spinal cord injury (SCI; age, 40 ± 6 years) and six able-bodied subjects (AB; age, 37 ± 8 years) volunteered to participate in the present study. The subjects consumed an identical test m...

GENE EXPRESSION ANALYSIS OF NEUROTROPHINS, TRK RECEPTORS, AND ASSOCIATED REGULATORY MOLECULES AFTER CONTUSIVE SPINAL CORD INJURY Matthew Tyler Hougland August 12, 2013 Traumatic spinal cord injury (SCI) results in changes to the anatomical, neurochemical, and physiological properties of cells in the central and peripheral nervous system. Neurotrophins, acting by binding to their cognate Trk rec...

The aim of the study was to investigate neurological outcome in road traffic accidents (RTA) with spinal cord injury (SCI). The study was undertaken in National Spinal Unit of Special Medical Rehabilitation Hospital, in Varazdinske Toplice, Croatia. Hospital records of 154 inpatient RTA SCI patients, in years 1991-2001 were reviewed. Six groups of patients were formed: car drivers, co-drivers, ...

During traumatic spinal cord injury (SCI), the spinal cord is subject to external displacements that result in damage of neural tissues. These displacements produce complex internal deformations, or strains, of the spinal cord parenchyma. The aim of this study is to determine a relationship between these internal strains during SCI and primary damage to spinal cord gray matter (GM) in an in viv...

Spinal cord injury is a devastating chronic condition resulting in temporary or permanent motor,sensory or autonomic dysfunction of the cord. The manifestation of spinal cord injury based onthe severity and involved areas could be different. Numerous studies have demonstrated thatbradycardia, hypotension, and orthostatic hypotension are present insignificant number ofpat...

Introduction. Spinal cord injury (SCI) remains a clinical challenge, despite multiple technologies to treat these injuries. Much of this difficulty lies in a lack of understanding of the factors required for neural regeneration once the cord is damaged or severed. Nonetheless, many techniques are currently being developed to promote neural regrowth after spinal cord injury, and animal models ar...

Spinal cord injury (SCI) is a devastating injury that leads to the total or partial loss of motor and sensory functions, but also affects the function of many body systems producing an almost total dependence and poor quality of life [1], although the level of the spinal cord in which the injury occurs and the degree of the injury are strong determinants of morbidity associated with the lesion....

Spinal cord injury (SCI) is a devastating neurologic disorder that often inflicts neuropathic pain, which further impacts negatively on the patient's quality of life. Endothelin peptides, which exert their effects via endothelin A (ETAR) and endothelin B (ETBR) receptors, can contribute to sensory changes associated with inflammatory and neuropathic pain, but their role in nociception following...

Introduction: Sex differences in outcomes of Spinal Cord Injury (SCI) suggest a sex-hormone-mediated effect on post-SCI pathological events, including glutamate excitotoxicity. This study aimed to investigate the importance of gonadal hormones on glutamate release subsequent to SCI in rats. Methods: After laminectomy at T8-T9, an electrolytic lesion was applied to the spinothalamic tracts of m...

Spinal cord injury (SCI) is a devastating disorder that often results in severe sensorimotor function impairment with limited recovery of function. In recent years, rehabilitation training for spinal has gradually emerged, and some them play an important role the repair However, optimal regimen SCI remains to be determined. this study, we explore effects rotarod (began at 7 days post-injury) on...