epidural abscess of the spinal column is a rare condition that can be fatal if left untreated. it promptly progresses and can cause neurologic paralysis, urinary retention or cauda equina syndrome. compromised immune system that occurs in patients with diabetes mellitus, aids, chronic renal failure, alcoholism, or cancer is a predisposing factor. it mostly occurs in adults. here we would like t...

Central nervous system is the main body of human system, composed brain and spinal cord, its function to transmit, store process information, produce a variety psychological activities, dominate control all animal behavior. When central diseases occur, people's ability information has problems, cognitive problems will such as aphasia, apraxia, agnosia, memory impairment, executive loss, reduced...

Low back pain is an important cause of referrals in the primary care setting. Overall, 85% initial admissions are considered to be nonspecific low that resolves a few weeks without need for additional evaluation. Myofascial pain, lumbar disc herniation, spinal stenosis, facet joint and degeneration, sacroiliac pathologies common causes mechanical pain. Non-mechanical includes infections vertebr...

background :cell-based therapies can be used to treat neurological diseases and spinal cord injuries. the aim of this study was to assess the clinical outcome of bone marrow derived mononuclear cells (bm-mncs) transplantation in patients with spinal cord injuries.   method s: following a systematic review to detect clinical intervention studies, a meta-analysis was done for pooling data to esti...

Lumbar disc herniation (LDH) is one of the most common spinal diseases. The surgical options can be open or minimally invasive which adopted according to condition patient. With development technology, endoscopic therapy has gradually become main option treat LDH. According situation patients with lumbar and its influence on peripheral nerves other tissues, combined advantages different options...

Objective(s): Neurotrophic factors secreting cells (NTS-SCs) may be a superior cell source for cell-based therapy in neurodegenerative diseases. NTS-SCs are able to secrete some neurotrophic Such as nerve growth factor and glia-derived neurotrophic factor. Our primary aim was to assess transplantation of neurotrophic factor secreting cells derived from human adipose-derived stem cells (hADSCs) ...

Background and Objective: Evaluation of degenerative changes of motoneurons and their related synapses can be useful in understanding the mechanisms of neurodegenerative diseases and their potential treatment. The present electron microscopic and immunohistochemical study investigates the axotomy-induced...