نتایج جستجو برای: spindle loading

تعداد نتایج: 102684  

2014
Dara S. Manoach Charmaine Demanuele Erin J. Wamsley Mark Vangel Debra M. Montrose Jean Miewald David Kupfer Daniel Buysse Robert Stickgold Matcheri S. Keshavan

INTRODUCTION Chronic medicated patients with schizophrenia have marked reductions in sleep spindle activity and a correlated deficit in sleep-dependent memory consolidation. Using archival data, we investigated whether antipsychotic-naïve early course patients with schizophrenia and young non-psychotic first-degree relatives of patients with schizophrenia also show reduced sleep spindle activit...

Journal: :Journal of cell science 2007
Rahul Pandey Sebastian Heeger Christian F Lehner

The dramatic chromosome instability in certain tumors might reflect a synergy of spindle checkpoint defects with hypoxic conditions. In Caenorhabditis elegans and Drosophila melanogaster, spindle checkpoint activation has been implicated in the response to acute anoxia. The activation mechanism is unknown. Our analyses in D. melanogaster demonstrate that oxygen deprivation affects microtubule o...

Journal: :Investigative ophthalmology 1972
T Iwamoto I S Jones G M Howard

Eight cases of uveal malignant melanoma were studied with the electron microscope with the purpose of comparing the ultrastructural features of the three basic cell types (spindle A, spindle B, and epithelioid) originally described by Callender under the light microscope. Five of the eight tumors were of pure cell type, and three were mixed. This was undertaken because of earlier diverse opinio...

Journal: :Journal of cell science 2012
Sylvain Meunier Isabelle Vernos

The mitotic spindle is structurally and functionally defined by its main component, the microtubules (MTs). The MTs making up the spindle have various functions, organization and dynamics: astral MTs emanate from the centrosome and reach the cell cortex, and thus have a major role in spindle positioning; interpolar MTs are the main constituent of the spindle and are key for the establishment of...

Journal: :Journal of cell science 2005
Stephen M Huisman Marisa Segal

In asymmetric divisions, the mitotic spindle must align according to the cell polarity axis. This is achieved through targeting astral microtubules emanating from each spindle pole to opposite cell cortex compartments. Saccharomyces cerevisiae is a powerful genetic model for dissection of this complex process. Intense research in this yeast has rendered detailed models for a program linking act...

Journal: :The Journal of Cell Biology 1975
E D Salmon

Changes in birefringence retardation (BR) and length of Chaetopterus meiotic metaphase-arrested spindles produced by increased hydrostatic pressure were observed with polarized-light microscopy using a newly developed optical pressure chamber. Increased pressure produced rapid, reversible decreases in spindle BR and length. Pressures of 3,500 psi or higher at 22 degrees C caused complete disapp...

Journal: :Lubricants 2023

Misalignment or unbalanced loading of machine tool spindle bearings often results in skewed bearing operation, which makes the more susceptible to failure. In addition, due weak impact signal a single feature information cannot accurately characterize operation status bearing. To address above problems, this paper proposes method monitor uneven running state load based on dual-channel fusion im...

Journal: :The Journal of Cell Biology 1999
Richard A. Heil-Chapdelaine Neil R. Adames John A. Cooper

I n higher eukaryotes, the position of cytokinesis is determined by the position of the mitotic spindle (Rappaport, 1990). Generally, the spindle sits in the middle of the cell and cytokinesis produces two equivalent cells. However, many developmental processes require specific positioning of the cleavage plane and, hence, the mitotic spindle. For example, control of spindle position can be use...

ژورنال: مواد پرانرژی 2021

Viscosity is one of the important parameters in design and production of composite solid propellants. Propellants with low end of mix (EoM) viscosity and longer pot-life have suitable condition for casting process. Several factors control the rheology behavior of propellants. In some cases, it may be necessary to apply some additives in order to optimize the rheology of the formulation. In this...

Journal: :Frontiers in bioscience : a journal and virtual library 2006
Wei-Hua Wang Qing-Yuan Sun

In mitosis, a spindle checkpoint plays important roles at the metaphase-anaphase transition to ensure the formation of a bipolar spindle, the completion of connecting chromosomes to microtubules and the alignment of all chromosomes at the spindle equator before initiation of anaphase. Components of the spindle checkpoint were first identified through genetic screens in budding yeast and some ch...

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