A novel bath lily-like graphene sheet-wrapped nano-Si composite synthesized via a simple spray drying process exhibits a high reversible capacity of 1525 mAh g(-1) and superior cycling stability, which could be attributed to a synergistic effect between highly conductive graphene sheets and active nanoparticles in the open nano/micro-structure."

0.6Li2MnO3-0.4Li(Ni1/3Co1/3Mn1/3)O2 composite microspheres with dense structures are prepared by a two-step spray-drying process. Precursor powders with hollow and porous structures prepared by the spray-drying process are post-treated at a low temperature of 400 °C and then wet-milled to obtain a slurry with high stability. The slurry of the mixture of metal oxides is spray-dried to prepare pr...

Removal of sludges from Wastewater Treatment Plants (WWTP) represents a serious worldwide environmental problem for which alternatives other than their simple incineration are investigated. In this work the treatment of raw sludge from urban WWTP by means of a minimization process through spray-drying is analyzed as well as some proposals for revaluating the resulting dry product. Analysis is s...

One of the advantages of dry influenza vaccines over conventional liquid influenza vaccines is that they can be used for alternative routes of administration. Previous studies showed that spray freeze-drying is an excellent technique to prepare vaccine containing powders for pulmonary delivery (J.P. Amorij, V. Saluja, A.H. Petersen, W.L.J. Hinrichs, A. Huckriede, H.W. Frijlink, Pulmonary delive...

Accepted March 11, 2009 The purpose of this study was to improve the solubility and dissolution rate of carvedilol by forming a ternary complex with b-cyclodextrin and citric acid and to formulate its mouth-dissolving tablets. The rationale for preparing mouth-dissolving tablet of carvedilol was to make the drug available in a soluble form in the mouth, which would facilitate its absorption fro...

Many studies have demonstrated the antioxidant activity and health benefits of the anthocyanins. The juice of Rubus sp. contains large amounts of anthocyanins and these flavonoids pigments give their characteristic color which tends to degrade easily, also its stability is affected during processing and storage, therefore spray drying can be used to avoid the degradation. The objective of the p...

Inhalation administration is a promising alternative to the invasive drug delivery methods. The particle size required for ideal drug aerosol preparation is between 1 and 3 μm. The application of microspherical particles of solid dispersions enhances bioavailability of poorly soluble drugs due to the solubilization. In the present work, the spray drying process of the production of microspheric...

This study evaluated the chemical properties (polyphenol and genistein contents) of soybean extracts obtained by biotransformation and dried by spray dryer at different conditions and their in vivo ability to inhibit 12-O-tetradecanoylphorbol-13-acetate- (TPA-) induced biochemical alterations in the skin of hairless mice. By comparing the obtained data with that of the well-known active soybean...

The objective of the present study was to develop self micro emulsifying formulation (SMEF) of valsartan to improve its oral bioavailability. The formulations were screened on the basis of solubility, stability, emulsification efficiency, particle size and zeta potential. The optimized liquid SMEF contains valsartan (20% w/w), Capmul MCM C8 (16% w/w), Tween 80 (42.66% w/w) and PEG 400 (21.33% w...

In this systematic and comprehensive study, inhalation powders of the polypeptide immunosuppressant drug - cyclosporine A - for lung delivery as dry powder inhalers (DPIs) were successfully designed, developed, and optimized. Several spray drying pump rates were rationally chosen. Comprehensive physicochemical characterization and imaging was carried out using scanning electron microscopy, hot-...