The exercise stress test (EST) is the commonest non-invasive test to elucidate the nature of chest pain/discomfort. ST segment depression provides evidence of ischemia, but is hampered by a significant number of false negative and false positive tests. This study evaluated patterns and duration of ST depression in an attempt to differentiate false positive and false negative tests. One hundred ...

OBJECTIVES This study aimed to determine the quantitative low-flow threshold for stress-induced perfusion defects with severe angina and/or significant ST-segment depression during dipyridamole hyperemia. BACKGROUND Vasodilator stress reveals differences in regional perfusion without ischemia in most patients. However, in patients with a perfusion defect, angina, and/or significant ST-segment...

BackgroundThe incidence and magnitude of cardiac ischemia arrhythmias in patients with chronic obstructive pulmonary disease (COPD) during exposure to hypobaric hypoxia is insufficiently studied. We investigated electrocardiogram (ECG) markers at rest incremental exercise testing (IET) COPD-patients travelling 3100 m.Study design methodsLowlanders (residence <800 m) COPD (forced volume the firs...

Effects of calcium antagonists on the ST alternans and associated mechanical alternans during acute coronary occlusion were examined in anesthetized dogs. The heart rate was fixed by atrial pacing. The intravenous administration of 0.2 mg/kg verapamil attenuated the ST alternans as did 0.5 mg/kg diltiazem. Although these drugs significantly attenuated TQ depression during occlusion, the attenua...