BACKGROUND The prevalence of hepatitis-C is on the rise in Pakistan. Treatment of chronic hepatitis-C with pegylated interferon is expensive as compared to standard interferon. The objective of the study was to find out the end treatment response rate with standard interferon and ribavirin. METHODOLOGy: This case series study was conducted in Ayub Teaching Hospital Abbottabad.and Orush General ...

The C++ Standard Template Library is the flagship example for libraries based on the generic programming paradigm. The usage of this library is intended to minimize classical C/C++ errors, but does not warrant bug-free programs. Furthermore, many new kinds of errors may arise from the inaccurate use of the generic programming paradigm, like dereferencing invalid iterators or misunderstanding re...

Ziv-Lempel and Crochemore factorization are two kinds of factorizations of words related to text processing. In this paper, we find these factorizations for standard epiesturmian words. Thus the previously known c-factorization of standard Sturmian words is provided as a special case. Moreover, the two factorizations are compared.

CRISPR-associated protein Cpf1 cleaves double-stranded DNA under the guidance of CRISPR RNA (crRNA), generating sticky ends. Because of this characteristic, Cpf1 has been used for the establishment of a DNA assembly standard called C-Brick, which has the advantage of long recognition sites and short scars. On a standard C-Brick vector, there are four Cpf1 recognition sites - the prefix (T1 and ...

Niemann–Pick C (NPC) disease is rare, neurodegenerative, lysosomal cholesterol storage disorder. Diagnosis of the disease is often delayed due to disease heterogeneity, non-specific early visceral and neurological symptoms, and lack of a rapid and reliable diagnostic assay. As a result, the disease progresses and opportunities to intervene tragically are lost. Until recently, the principal diag...

IT products developed without due consideration of security issues have caused many security accidents over the last ten years. As a result, the importance of security in software development is increasing. It is important to ensure that no known vulnerabilities remain in the design, development, and test stage, in order to develop secure IT products. Even when an IT product is designed securel...

Modern programmers must exploit parallelism for performance gains, possibly through the use of an attached or on-chip GPU. To take advantage of the GPU in C++ programs, the programmer must use either a new language (CUDA or OpenCL) or an external library (Thrust). Rather than requiring that programmers learn new tools, modify existing code, and change software development practices, the C++ Sta...

The standard of care for treatment of individuals chronically infected with hepatitis C virus is pegylated interferon in combination with ribavirin. Efficacy is closely related to viral genotype. This review outlines potential therapeutic strategies for treatment failures and discusses some of the newer agents currently in development.

The C++ Standard Template Library is a widely-used library that is based on the generic programming paradigm. The usage of this library does not warrant bug-free programs. Furthermore, many new errors may arise from the inaccurate use of the generic programming paradigm, like dereferencing invalid iterators or misunderstanding remove-like algorithms. Most of the STL algorithms have precondition...