The premium calculation principle is one of the main objectives of study for actuaries. There seems to be full agreement among the leading theoreticians in the field that the insurance premium should reflect both the expected claims and certain loadings. This is true for policy, risk or portfolio. There are three types of positive loadings: a) a loading to cover commissions, administrative cost...

The purpose of this study was to investigate how different footwear (highly cushioned, standard, minimalist shoes) affect peak ground reaction forces, average loading rates and joint kinematics during running. Nine participants ran at a self-selected speed across all shod conditions, minimalist, highly cushioned and standard running shoe. Vicon Nexus was used to analyze joint kinematics of the ...

Evidence suggests that there is shared genetic aetiology across the major psychiatric disorders conferred by additive effects of many common variants. Measuring their joint effects on brain function may identify common neural risk mechanisms. We investigated the effects of a cross-disorder polygenic risk score (PGRS), based on additive effects of genetic susceptibility to the five major psychia...

In recent history there has been an enormous development in the subject area of Power Line Communications (PLC), since it has become possible due to advanced digital communications and digital signal processing techniques to use power lines for data transmission. PLC allows the use of the dynamic and far-reaching power cables to support high speed communication capabilities. Discrete Multi-tone...

Failure diagnosis invariably involves consideration of both associated material condition and the results of a mechanical analysis of prior operating history. This Review focuses on these aspects with particular reference to creep-fatigue failure diagnosis. Creep-fatigue cracking can be due to a spectrum of loading conditions ranging from pure cyclic to mainly steady loading with infrequent off...

Antiplatelet therapy could prevent stent thrombosis, but may be associated with an increased risk of bleeding. Recent studies have revealed that bleeding complications are relatively frequent in patients with acute coronary syndromes. Our aim was to describe the current status of antiplatelet therapy for Japanese patients with acute myocardial infarction (AMI). The Japan AMI (J-AMI) registry is...

Fifth metatarsal stress fractures are common in sports and often result in delayed and non-union. The purpose of this study was to examine the effect of a rigid carbon graphite footplate (CGF) on plantar loading during take-off and landing from a jump. Nineteen recreational male athletes with no history of lower extremity injury in the past 6 months and no foot or ankle surgery in the past 3 ye...

PURPOSE To experimentally validate a non-linear finite element analysis (FEA) modeling approach assessing in-vitro fracture risk at the proximal femur and to transfer the method to standard in-vivo multi-detector computed tomography (MDCT) data of the hip aiming to predict additional hip fracture risk in subjects with and without osteoporosis associated vertebral fractures using bone mineral de...

Among the subgroups of agricultural workers, nursery workers have previously been identified as a group at high risk for occupational skin disease. Review of available surveillance information on nursery skin illnesses has also demonstrated that provocation patch testing is performed in less than 1% of the reported cases. We tested reactions to a battery of pesticides, plants, and the standard ...

Unreinforced masonry (URM) structures are known to be rather vulnerable to seismic loading. Modern URM buildings with reinforced concrete (RC) slabs might, however, have an acceptable seismic performance for regions of low to moderate seismicity. In particular in countries of moderate seismicity it is often difficult to demonstrate the seismic safety of modern URM buildings by means of force-ba...