The staphylococcidal capability of populations of peritoneal macrophages in rabbits has been measured before and after repeated infections with Staphylococcus aureus. Such rabbits after infection showed delayed-type hypersensitivity to S. aureus antigens, but the staphylococcidal capability of the peritoneal macrophages was not increased. This result at the cellular level is in agreement with p...

It has become apparent in recent years that exposure to the hospital environment can give rise to serious, sometimes fatal infection by hemolytic staphylococci. It is the purpose of this report to present data on the incidence of staphylococcal disease in human populations and to review evidence for unusual virulence in man of so-called hospital staphylococci. Among many factors which have been...

The course of infection in a 3-week-old premature newborn suffering from extensive dermatitis with flaccid blisters is described. Staphylococcus aureus was recovered from a local wound infection around a chest tube inserted to drain a postoperative chylothorax. The strain isolated tested positive for the eta gene for exfoliative toxin A, the causative agent of staphylococcal scalded-skin syndro...

When Staphylococcus aureus penetrates the epidermis and reaches the dermis, polymorphonuclear leukocytes (PMLs) accumulate and an abscess is formed. However, the molecular mechanisms that orchestrate initiation and termination of inflammation in skin infection are incompletely understood. In human myeloid differentiation primary response gene 88 (MyD88) deficiency, staphylococcal skin and soft ...

Background: Urinary tract infection (UTI) is a condition, which manifest in various forms such as acute, uncomplicated bacterial pyelonephritis, complicated UTI, recurrent cystitis and asymptomatic bacteriuria. Urinary tract infection (UTI) is one of the most frequent types of bacterial infections. The main purpose of this study was to determinate the frequency and antibiogram profile of Staphy...

Objectives: Staphylococcus aureus is an important pathogen associated with diseases in a variety of hosts including humans. It produces several toxins and virulence factors that contribute to its pathogenic potential such as staphylococcal enterotoxins (SEs). This study was conducted to determine enterotoxigenicity of S. aureus associated with chronic urogenital tract infection by detecting ent...

During the 1950s, Staphylococcus aureus became a major source of hospital infections and death, particularly in neonates. This situation was further complicated by the fact that Staphylococcus quickly gained resistance to most antibiotics. Controlling these infections was a pressing concern for hospital workers, especially bacteriologists who tackled it through the use of a new epidemiologic to...

Antibiotic-resistant Staphylococcus aureus is of great concern, as it causes a wide range of life-threatening infections. The current study demonstrates that dihydropyrrolone (DHP)-coated polyacrylamide substrates are effective in reducing the number of culturable clinical isolates of S. aureus in vitro in a dose-dependent manner and are able to reduce the pathogenic potential of staphylococcal...

The combination of levofloxacin and rifampin has been recommended for the treatment of staphylococcal prosthetic infection. In a rabbit model of prosthetic knee infection due to a susceptible clinical strain of Staphylococcus aureus, the combination of levofloxacin and rifampin was bactericidal, significantly reduced bacterial titers in bone compared with levels for rifampin and controls (P < 0...

One month after a 21-year-old female drug addict with tricuspid staphylococcal endocarditis seemed to have been cured by antibiotic therapy she relapsed. Further antibiotic treatment for one month failed to control the infection. Tricuspidectomy was when performed and the infection was eliminated. A valve prosthesis was inserted 3 months later. She recovered and is now fully restored to health....