نتایج جستجو برای: starvation stress
تعداد نتایج: 449778 فیلتر نتایج به سال:
The cytoplasmic fate of mRNAs is dictated by the relative activities of the intimately connected mRNA decay and translation initiation pathways. In this study, we have found that yeast strains compromised for stages downstream of deadenylation in the major mRNA decay pathway are incapable of inhibiting global translation initiation in response to stress. In the past, the paradigm of the eIF2alp...
The complete genome sequence of the radiation-resistant bacterium Deinococcus radiodurans R1 is composed of two chromosomes (2,648,638 and 412,348 base pairs), a megaplasmid (177,466 base pairs), and a small plasmid (45,704 base pairs), yielding a total genome of 3,284, 156 base pairs. Multiple components distributed on the chromosomes and megaplasmid that contribute to the ability of D. radiod...
Plants have evolved an array of responses that adapt their growth to conditions of limited phosphate (Pi) supply. These involve biochemical and developmental changes that improve Pi acquisition and recycling, and protect against the stress of Pi starvation. The induction of these responses requires a sophisticated regulatory system that integrates information on external and internal plant Pi s...
Cytosine DNA methylation (mC) is a genome modification that can regulate the expression of coding and non-coding genetic elements. However, little is known about the involvement of mC in response to environmental cues. Using whole genome bisulfite sequencing to assess the spatio-temporal dynamics of mC in rice grown under phosphate starvation and recovery conditions, we identified widespread ph...
Mitochondria respond to environmental cues and stress conditions. Additionally, the disruption of the mitochondrial network dynamics and its distribution is implicated in a variety of neurodegenerative diseases. Here, we reveal a new function for Myo19 in mitochondrial dynamics and localization during the cellular response to glucose starvation. Ectopically expressed Myo19 localized with mitoch...
The pathophysiology of glucose metabolism in critical illness is a complex spectrum ranging from protein calorie malnutrition and starvation of the one hand, to a hypermetabolic response engendered by injury, inflammation and infection on the other. In their pure state, the two can exhibit almost diametrically opposite pathophysiological changes. An understanding of the hormonal, cytokine and g...
A novel uncoupling protein, UCP5, has recently been characterized as a functional mitochondrial uncoupler in Drosophila. Here we demonstrate that UCP5 knockout (UCP5KO) flies are highly sensitive to starvation stress, a phenotype that can be reversed by ectopic neuronal expression of UCP5. UCP5KO flies live longer than controls on low-calorie diets, have a decreased level of fertility, and gain...
The traditional variable selection problem has attracted renewed attention from statistical researchers due to the recent advances in data collection, especially in fields such as bioinformatics and marketing. In this paper, we formulate regression variable selection as an optimization problem, propose and study several deterministic and stochastic sequential optimization methods with lookahead...
The present paper deals with the influence of starvation on fish which has great ability to adapt in starvation stress. In the present investigation, the effect of prolonged food deprivation on ascorbic acid contents of gonadal tissues has been observed in both the sexes of Clarias batrachus. The level of ascorbic acid content was found relatively higher in males than in females. The testes sho...
Bacteria become highly tolerant to antibiotics when nutrients are limited. The inactivity of antibiotic targets caused by starvation-induced growth arrest is thought to be a key mechanism producing tolerance. Here we show that the antibiotic tolerance of nutrient-limited and biofilm Pseudomonas aeruginosa is mediated by active responses to starvation, rather than by the passive effects of growt...
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