Fifty patients presenting with first episode genital herpes were randomly allocated to seven day treatment with either oral acyclovir plus 5% acyclovir cream or oral acyclovir plus matching placebo cream. Combined treatment with oral and topical acyclovir was associated with a shorter duration of itching in women alone (p = 0.04) but gave no clinical relief of other symptoms, the time to healin...

A 29-year-old female, an aesthetician, developed occupational allergic contact dermatitis caused by extracts of crude drugs. The results of 48-hour closed patch testing showed positive reactions to the moisturizing cream and oil that she used in her work. This cream and oil included Scutellraria Baicalensis, mugwort (Artemisia vulgaris), and Artemisia capillaris,Gardenia. The results of patch t...

Ice cream is the major dairy product that dominates interest of large segments of the population. As a result, its production and consumption are rapidly increasing. The microbiological quality of ice cream during retail marketing mainly depends on the contamination during the product handling as well as efficiency and sanitary conditions during frozen storage. Many food poisoning cases associa...

A reversed-phase liquid chromatographic method for the determination of 1,7,7-trimethyl-bicyclo(2,2,1)heptan-2-one in a cream formulation is developed and validated. The separation was achieved using an isocratic mobile phase, on a Lichrosorb C8 column. The calibration curve is linear (r(2)= 0.9999) from 25-175% of the analytical concentration of 1.0 mg/ml. The mean percent standard deviation v...

Imiquimod is an immunomodulator with both antitumor and antiviral properties. It is currently available in two cream formulations as Aldara (imiquimod 5%) and the newly approved Zyclara (imiquimod 3.75%). Imiquimod has been associated with localized erythema, crusting, and scaling at the site of application. However, more severe generalized skin eruptions including erythema multiforme, psoriasi...

Thrombophlebitis is a common complication of intravenous therapy with incidence of 24% to 29% (3, 6), which is rarely serious but the pain is often vc-ry bothersome (I). To minimise infusion phlebitis, various measures have been suggested (6). Woodhouse (8) used 'Movelat cream', as a preventive measure, containing I% adrenocortical extract, 0.2'" organoheparinoid, 22% salicylic acid in cream ba...

A 34-year-old woman developed nephrotic syndrome after using a skin lightening cream that contained an extremely high level of mercury. Blood and urine mercury levels were elevated and a renal biopsy revealed minimal change disease. Membranous nephropathy was excluded using immunofluorescence and electron microscopy. Her proteinuria remitted 9 months after she stopped using the cosmetic cream. ...

Consider the following scenario: Every day before work, you stop at a neighborhood coffee shop and order a cup of coffee with cream and no sugar. This scenario repeats itself for years without incident. Then one day, after you drive away with your coffee, you notice that the workers forgot the cream and put in sugar instead. The next day you mention the mistake, and the coffee shop manager apol...

BACKGROUND Herpes simplex virus infection (HSV) is a common and ubiquitous infection of the skin which causes mucocutaneous lesions called cold sores (herpes labialis) or fever blisters. It is estimated that approximately 80% of the population worldwide are carriers of the Herpes simplex virus, approximately 40% suffer from recurrent recurrent infections. This study evaluates the in vitro skin ...