Raspberry ketone (RK) has high commercial value in the food and healthcare industries. A biological route to this flavour compound is an attractive prospect, considering need meet consumer demands sustainable goals; however, it yet become industrial reality. In work, fungal production of raspberry compounds (RC) via submerged fermentation Nidula niveo-tomentosa was characterized flask, stirred-...

RESEARCH ARTICLE Intensifying the Fermentation of Aspergillus oryzae in a Stirred Bioreactor Using Maxblend Impeller Narges Ghobadi, Chiaki Ogino and Naoto Ohmura Department of Chemical Science and Engineering, Graduate School of Engineering, Kobe University 1-1 Rokkodaicho, Nada-ku, Kobe 657-8501, Japan Department of Chemical Science and Engineering, Graduate School of Engineering, Kobe Univer...

Continuous Stirred Tank Reactor (CSTR) is one of the common reactors in chemical process and all industrial process requires a solution of specific chemical strength of chemicals considered for analysis. In this paper, Particle Swarm Optimization (PSO) algorithm based PID controller tuning is attempted for the concentration control of Continuous Stirred tank reactor (CSTR). The Modeling can be ...

Enzyme catalysis in two-phase systems, particularly in the functionalization of siloxanes, is a new challenge for biocatalysis. On the basis of three different reaction systems, stirred tank reactor, enzyme membrane reactor and micro mixer, the influence of the phase boundary layer along the interface between an aqueous system and an organosiloxane on the synthesis of hydroxyalkylfunctionalized...

Increasing interest in the production of second-generation ethanol necessitates the low-cost production of enzymes from the cellulolytic complex (endoglucanases, exoglucanases, and β-glucosidases), which act synergistically in cellulose breakdown. The present work aimed to optimise a bioprocess to produce these biocatalysts from the fungus Penicillium funiculosum ATCC11797. A statistical full f...

Continuous Stirred Tank Reactor (CSTR) plays an important role in the process industries. It helps for maintaining the temperature of the liquid in the reactors. This paper deals with the comparison of adaptive control and conventional PID control in CSTR process. In the adaptive control, Model Reference Adaptive Control (MRAC) and Self-Tuning Regulator (STR) methods are used. The Recursive Lea...

Background Human cell lines are an interesting alternative to CHO cells for the production of recombinant proteins and monoclonal antibodies, because of their ability to produce genuine human posttranslational modifications. The human cell line AGE1.HN.AAT (ProBioGen, Berlin, Germany), that originated from human neural precursor tissue, has been adapted to serum-free conditions and cultivated i...

A previously developed immobilization technique involving agar as matrix is investigated further in penicillin production by P. chrysogenum ATCC 10238 at reactor level. Several modifications were found to decrease the germination lag time, including a higher spore concentration, an increased porosity of gel, and decreasing the mass transfer barrier. This approach enabled the production of penic...

Bacillus amyloliquifaciens SH8 has been explored as a potential xylanolytic in-house producer for xylanase production in a bioreactor by optimizing process conditions. The scale-up of the fermentation process up to 3.5 L along with the optimization of physical parameters yielded a significantly increased xylanase yield – of 67.80 IU/mL, in 8 h of fermentation at an inoculum size of 10% with an ...

Multistep and continuous production of core–shell InP/ZnS semiconductor nanocrystals in a high-temperature miniature stirred-tank reactor cascade.