The dynamical solution of a well-mixed, nonlinear stochastic chemical kinetic system, described by the Master equation, may be exactly computed using the stochastic simulation algorithm. However, because the computational cost scales with the number of reaction occurrences, systems with one or more "fast" reactions become costly to simulate. This paper describes a hybrid stochastic method that ...

This report is a survey of existing tools for the analysis and the simulation of stochastic hybrid systems. Given the high degree of generality of the stochastic hybrid framework and the relative novelty of the field, few full-blown, broadly applicable tools are expected to exist. Literature review confirmed this idea. Most of the available techniques dedicated to stochastic hybrid systems anal...