Gastrointestinal stromal tumours (GIST) comprise a heterogeneous group of the most common mesenchymal neoplasms gastrointestinal tract. The majority GIST are induced by activating, mutually exclusive mutations two genes – KIT and PDGFRA (platelet-derived growth factor receptor-alpha). However, approximately 10–15% GISTs lack oncogenic or these often called “wild type” (WT) GISTs. SDH-deficient ...

Esophagogastric junction cancer is the 4th most common cancer in humans. Gastric adenocarcinomas are the most common histopathological type of gastric tumors, with the others constituting 5% of tumors (1,2). Combined tumors can be synchronous, composite, or collision tumors. Collision tumors are non-intermingling contiguous tumors of two or more different histopathological types. Here we report...

Malignant gastrointestinal stromal tumors (GISTs) are rare non-epithelial, mesenchymal neoplasms of the gastrointestinal tract that metastasize or recur in 30% of patients who undergo surgical resection with curative intent. A 59-year-old man visited our hospital for an examination of a palpable mass in the left abdomen. Fourteen months prior to his visit, the patient underwent gastric wedge re...

Gastrointestinal mesenchymal tumors are a group of tumors originated from the mesenchymal stem cells of the gastrointestinal tract, consisting of gastrointestinal stromal tumors (GIST), leiomyomas or leiomyosarcomas or schwannomas. Gastric schwannoma is a very rare gastrointestinal mesenchymal tumor, which represents only 0.2% of all gastric tumors and 4% of all benign gastric neoplasms. We rep...

Schwannomas, or neurinomas, are generally benign, slow-growing, asymptomatic neoplasms originating from the Schwann cells of a nerve sheath. As a part of spindle cell mesenchymal tumours, schwannomas arising from the gastrointestinal tract (GIT) are unusual; however, when they occur, the most common site involved is the stomach, which represents 0.2% of all gastric tumours. We report the case o...

Familial adenomatous polyposis (FAP) is characterised by hundreds of colorectal adenomas. Endocrine neoplasms have occasionally been reported, as have gastric polyps, which are usually hamartomatous in the fundus of the stomach and adenomatous in the antrum. A 57 year old man with colorectal, gastric, and periampullary adenomatous polyposis, in association with three bilateral adrenocortical ad...

We report a case of multiple gastric carcinomas associated with Potter type III cystic disease of the liver, mesenterium and kidney. A 65-year-old man with chronic renal failure due to polycystic kidneys and under hemodialysis treatment 3 times a week for 2 years was admitted to our hospital because of anemia. He stated that his sister had suffered from polycystic kidney disease. Gastrointestin...

Gastric glomus tumor is a rare neoplasm of the gastrointestinal tract that frequently mimics other mesenchymal lesions clinically and radiologically. We present a 70-year-old woman with an incidentally detected submucosal tumor of the antrum that was thought to be a gastrointestinal stromal tumor (GIST). The lesion measured 1.9 cm radiographically and was monitored over a period of 3 years. Mul...

The modifying roles of age, sex, and strain of mice on the incidence, multiplicity, and spectrum of tumors induced by benzo(a)pyrene have been investigated. The first-generation (F1) hybrids of C57BL/6J X C3HeB/FeJ and C3HEB/Fej X A/J mice of both sexes were given single i.p. injections (75 or 150 mug/g) of benzo(a)pyrene at 1, 15, or 42 days of age. Experimental animals were allowed to live th...

published by admin on Mon, 08/19/2013 12:59pm Title Wedge resection for gastric submucosal tumors. Publication Type Journal Article Year of Publication 2011 Authors Albright, JB, McGwin, G Journal J Am Coll Surg Volume 213 Issue 3 Pagination 452; author reply 453 Date Published 2011 Sep ISSN 1879-1190