After the application in vitro of (14)C amylopectin sulphate solution to frozen sections of human ulcer-bearing stomach, autoradiography demonstrates localization of amylopectin sulphate to the gastric surface. The affinity of amylopectin sulphate macromolecule for the gastric luminal surface would provide a substrate-bound pepsin inhibitor with a molecular sieve-like action to exclude proteoly...

Ulcer is the lesion that pierces the muscularis mucosa which does not show the tendency to heal. Its etiology mainly includes imbalance between offensive and protective factors in mucosa of stomach such as mucosal barriers, cellular regeneration, acid-pepsin secretion, blood flow and epidermal growth factors (Lima et al., 2006). This imbalance usually happened as consequence of H. pylori infect...

BACKGROUND/AIMS We aimed to determine the etiology of patients with duodenal and gastric ulcers. METHODS 140 patients diagnosed with peptic ulcer between April 2002-2009 were enrolled in this prospective study. Two biopsy specimens were collected from the antrum and corpus for histology and one for rapid urease testing, and stool samples were analyzed for Helicobacter pylori antigen. Serum ca...

Actinodaphne sesquipedalis Hook. F. Var. Glabra (Kochummen), also known as "Medang payung" by the Malay people, belongs to the Lauraceae family. In this study, methanol leaf extract of A. sesquipedalis was investigated for their acute toxicity and gastroprotective effects to reduce ulcers in rat stomachs induced by ethanol. The rats were assigned to one of five groups: normal group (group 1), u...

Glycyrrhiza glabra L. is used in folk medicine for treatment of stomach disorders includingpeptic ulcers. The hydroalcoholic extract of Glycyrrhiza glabra L. (HEGG) was evaluated forantiulcerogenic activity and acute toxicity profile in mice. Various doses of HEGG (50-200mg/kg) were administered orally to animals of different groups. Omeprazole and cimetidine atdoses of 30 and 100 mg/kg were us...

The topics of stomach and duodenum have been described in this report. The discovery of Helicobacter pylori was the revolutionary event in the pathogenesis, diagnosis as well as treatment of gastrointestinal diseases. The eradication of the bacteria prevented the recurrence of peptic ulcer, namely gastric and duodenal ulcer. It is reported that this bacteria may be the main cause of gastric can...

Helicobacter pylori is a unique organism which is pathogenic for stomach-duodenum (chronic gastritis, duodenal ulcer, gastric ulcer, gastric malignancy, mucosa-associated lymphoid tissue (MALT) lymphoma) and protective for oesophagus (Barrett's oesophagus, oesophageal adenocarcinoma) at the same time in an individual. For prevention of diseases, the necessity of presence of some bacteria throug...

Equine Gastric Ulcer Syndrome (EGUS) and Right Dorsal Colitis (RDC) are common in performance horses. Diagnoses are based on history, clinical signs, laboratory findings, gastroscopic examination, and response to altered diet and medical therapy. Effective treatment strategies for EGUS focus on increasing stomach pH by inhibiting or buffering gastric acid, which allows a permissive environment ...

Helicobacter pylori bacteria reside in the mucosal lining of the stomach where, due to a variety of factors, the infection predisposes patients to peptic ulcer disease. Detection of H. pylori is important in the treatment and follow-up of patients with peptic ulcer disease and the urea breath test is the method of choice. This article will briefly review the methods for diagnosing H. pylori, em...

Introduction: Gastritis or ulcer disease is a very disturbing disease. This gastritis usually occurs in people who have irregular eating patterns and eat foods that can stimulate the production of stomach acid. more common teenagers, especially teenage girls often like to procrastinate eating. If not treated immediately, it will cause dangerous complications such as upper gastrointestinal bleed...