background the search for novel antibiotics continues to be of immense importance in research programs around the world for pharmaceutical, industrial and agricultural applications. filamentous soil bacteria, belonging to the streptomyces genus, are widely used as an important biological tool for their ability to produce a wide range of novel secondary metabolites, such as “antibiotics”. object...

Based on elementary mode analysis, an Escherichia coli strain was designed for efficient conversion of glycerol to ethanol. By using nine gene knockout mutations, the functional space of the central metabolism of E. coli was reduced from over 15,000 possible pathways to a total of 28 glycerol-utilizing pathways that support cell function. Among these pathways are eight aerobic and eight anaerob...

Abstract: In order to predict hot deformation behavior of superalloy nimonic 80A, a back-propagational artificial neural network (BP-ANN) and strain-dependent Arrhenius-type model were established based on the experimental data from isothermal compression tests on a Gleeble-3500 thermo-mechanical simulator at temperatures ranging of 1050–1250 ̋C, strain rates ranging of 0.01–10.0 s ́1. A comparis...

This article introduces a two-strain spatially explicit SIS epidemic model with space-dependent transmission parameters. We define reproduction numbers of the two strains, and show that the disease-free equilibrium will be globally stable if both reproduction numbers are below one. We also introduce the invasion numbers of the two strains which determine the ability of each strain to invade the...

The ability to actively control the shape of aerospace structures has initiated research regarding the use of Shape Memory Alloy actuators. These actuators can be used for morphing or shape change by controlling their temperature, which is effectively done by applying a voltage difference across their length. The ability to characterize this temperature-strain relationship using Reinforcement L...

In the space experiment "Molecular adaptation strategies of microorganisms to different space and planetary UV climate conditions" (ADAPT), bacterial endospores of the highly UV-resistant Bacillus subtilis strain MW01 were exposed to low-Earth orbit (LEO) and simulated martian surface conditions for 559 days on board the European Space Agency's exposure facility EXPOSE-E, mounted outside the In...

Background. While significant attention has been paid to the potential risk of pathogenic microbes aboard crewed spacecraft, the non-pathogenic microbes in these habitats have received less consideration. Preliminary work has demonstrated that the interior of the International Space Station (ISS) has a microbial community resembling those of built environments on Earth. Here we report the resul...

Probing the mechanisms of defect-defect interactions at strain rates lower than 10(6) s(-1) is an unresolved challenge to date to molecular dynamics (MD) techniques. Here we propose an original atomistic approach based on transition state theory and the concept of a strain-dependent effective activation barrier that is capable of simulating the kinetics of dislocation-defect interactions at vir...

The Verwey transition in Fe3O4 is the first metal-insulator transition caused by charge ordering. However, the physical mechanism and influence factors of Verwey transition are still debated. Herewith, the strain effects on the electronic structure of low-temperature phase (LTP) Fe3O4 with P2/c and Cc symmetries are investigated by first-principles calculations. LTP Fe3O4 with each space group ...