Central to the pathology of falciparum malaria is a reduction in the deformability of the infected red blood cells (RBCs). To enable improved methods to study this disease, we developed a microfluidic device to measure the deformability of infected cells. Individual RBCs are first infused into a series of funnel shaped constrictions. The deformability of individual cells is measured using the p...

Successful therapy of tumors with lymphokine-activated killer (LAK) cells is presumably dependent on their cytolytic potential and their gaining access to the target cells through the microcirculation. The latter process involves dissemination through the microvessels, adhesion to the venular walls, and extravasation through them, all of which depend on the size and deformability of these effec...

Successful therapy of tumors with lymphokine-activated killer (LAK) cells is presumably dependent on their cytolytic potential and their gaining access to the target cells through the microcirculation. The latter process involves dissemination through the microvessels, adhesion to the venular walls, and extravasation through them, all of which depend on the size and deformability of these effec...

To the Editor. We have read with interest the recently published article by Wiewióra et al. [7] regarding hemorheological differences related to gender in morbidly obese subjects. In this study authors found several hemorheological differences between male and female. In this sense, males showed higher blood viscosity and higher erythrocyte deformability than females and native blood viscosity ...

Metallic glasses (MGs) typically have high yield strength while low ductility, and the latter is commonly considered as the Achilles' heel of MGs. Elucidate the mechanism for such low ductility becomes the research focus of this field. With molecular level simulations, we show the degree of short-range order (SRO) of atomic structure for brittle Fe-based glass decreases dramatically during the ...

The purpose of this study was to characterize red blood cell (RBC) deformability by iron deficiency. We measured RBC deformability to ektacytometry, a laser diffraction method for determining the elongation of suspended red cells subjected to shear stress. Isotonic deformability of RBC from iron-deficient human subjects was consistently and significantly lower than that of normal controls. In g...

abstract surface soil shear strength is an effective parameter in soil erosion and runoff modeling, and known as soil erodibility index. this study was conducted to investigate and predict soil shear strength in central zagros region using multiple linear regressions (mlr). the study site was selected in rangeland and degraded-rangeland landuse with an area of 23562 ha. based on the maps of geo...

The effect of perfluorochemical blood substitutes (eg, Oxypherol or Fluosol-DA) on red cell deformability was investigated because these emulsions are in direct contact with red cells when they are used as temporary circulatory aids. Erythrocyte deformability was assessed by a constant volumetric flow rate filtration method. The results of in vitro incubation experiments indicate that perfluoro...