After publication of this Research [1], we noted that there is a misspelling in the name of Mogens Killian. Furthermore, we noted errors to Additional File 1, Table S1. For the strain S. pneumoniae AP200, the ‘Location of isolation’ should be ‘Italy’ rather than ‘University of Siena’. Also, in the Acknowledgements, we should have thanked all the AP200 genome project participants for providing e...

A genomic expression library of Streptococcus pneumoniae was screened with a convalescent-phase serum for immunoreactive proteins. Six known and 17 unknown pneumococcal proteins were detected. Five of the known proteins were surface-located virulence factors, and eight of the unknown proteins were putative membrane proteins.

Platelet-activating factor (PAF) is a critical mediator of severe inflammatory diseases such as pneumonia, and the PAF-receptor (PAFR) is known to be an anchor for Streptococcus pneumoniae attachment to lung epithelial cells. We conducted a DNA microarray analysis to detect critical factors that mediate fulminant pneumonia due to influenza virus and S. pneumoniae co-infection in mice. Among the...

November 12th marks the eighth annual World Pneumonia Day, observed to raise awareness of pneumonia as a global public health concern for persons of all ages and a leading infectious cause of death of children aged <5 years, causing approximately 900,000 child deaths annually (1). In the United States, the majority of the 53,000 annual pneumonia deaths occur in persons aged ≥65 years. Respirato...

We report here the draft genomes of two pneumococcal isolates in Hong Kong, CU_SPNE1_05 and CU_SPNE32_06. Strain CU_SPNE1_05 had a cefotaxime MIC of 1 µg/ml, and CU_SPNE32_06 had an MIC of 32 µg/ml. Both strains belong to the multidrug-resistant serogroup 19, sequence type 271 (clonal complex 3200/271).

We correlated outpatient antibiotic use with prevalence of penicillin-nonsusceptible Streptococcus pneumoniae (PNSP), macrolide-resistant S. pneumoniae (MRSP), and macrolide-resistant S. pyogenes (MRGAS) in 20 countries. Total antibiotic use was correlated with PNSP (r = 0.75; p < 0.001), as was macrolide use with MRSP (r = 0.88; p < 0.001) and MRGAS (r = 0.71; p = 0.004). Streptococcal resista...

The aim of this study was to describe the frequency positive Aspergillus tests in COVID-19 patients and investigate association between a test result. We compared proportion admitted intensive care unit (ICU) for &gt;24 h with two control groups: community-acquired pneumonia (i) PCR-confirmed influenza infection (considered since link invasive aspergillosis has been established) (ii) Streptococ...

The innate immune system employs C-type lectin receptors (CLRs) to recognize carbohydrate structures on pathogens and self-antigens. The Macrophage-inducible C-type lectin (Mincle) is a FcRγ-coupled CLR that was shown to bind to mycobacterial cord factor as well as certain fungal species. However, since CLR functions during bacterial infections have not yet been investigated thoroughly, we aime...

Troisier and Monaldi (Rg. Med., 1932, 96), having changed Lowenstein's method, performed blood cultures of patients who had one or another infectious disease. A.a. describe 3 cases, from the which VC were cultivated: 1st patient with endocarditis (blood culture produced non-hemolytic streptococcus) died septic cerebral infarction, autopsy did not reveal a single tbc focus. Nth. Croupous pneumon...