Investment traits--the tendency to seek out and engage in cognitive activity--might affect intellectual growth across the life span, specifically the development from fluid to crystallized intelligence. Here we explore how childhood IQ at age 11 years, IQ at age 79, and the investment trait Typical Intellectual Engagement (TIE) at age 81 affect the mean level and change in verbal fluency scores...

Little attention has been given to the measurement of the concept of tie strength. Using survey data on friendship ties, we apply multiple indicator techniques to construct and validate measures of tie strength. We conclude that: (1) there may be two distinct aspects of tie strength, having to do with the time spent in a relationship and the depth of the relationship; (2) a measure of "closenes...

One hundred and eighteeeee!! Amazing. I've just managed to break my New Year's resolutions in one fell swoop. The bottle of wine is empty, so is the box of doughnuts , and I'm still on the couch. It's nonsense trying to make lifestyle changes in January. The days are short and cold, the paperwork pile is still here from last year, and the waiting room is stuffed with miserable people who like m...

Angiopoietins are ligands of the Tie2 receptor that control angiogenic remodeling in a context-dependent manner. Tie signaling is involved in multiple steps of the angiogenic remodeling process during development, including destabilization of existing vessels, endothelial cell migration, tube formation and the subsequent stabilization of newly formed tubes by mesenchymal cells. Beyond this crit...

Continuous efforts have been made to find an effective treatment to improve oncologic outcomes for patients with colorectal cancer. These efforts have accomplished a noticeable achievement by using biomarker-based approaches. Antiangiogenic drugs that target the vascular endothelial growth factor (VEGF) signaling pathway have successfully expanded clinical treatment options for many cancer type...

A combined analysis of multiple terrestrial laser scanner point clouds recorded from different positions requires a geometric registration of these scans. In most applications of terrestrial laser scanning, artificial tie points, which can be recognized automatically by proprietary scanner software, are placed in the scanning area. In this case, the scan positions have to be chosen in a way tha...

abstract in this paper, a fuzzy pid with new structure is proposed to solve the load frequency control in interconnected power systems. in this study, a new structure and effective of the fuzzy pid-type load frequency control (lfc) is proposed to solve the load frequency control in interconnected power systems. the main objective is to eliminate the deviations in the frequency of different area...

An aluminum bow-tie nano-antenna is combined with the resonance Raman effect in the deep ultraviolet to dramatically increase the sensitivity of Raman spectra to a small volume of material, such as benzene used here. We further demonstrate gradient-field Raman peaks for several strong infrared modes. We achieve a gain of [Formula: see text] in signal intensity from the near field enhancement du...

The TIE-GCM simulator of the upper atmosphere has a number of features that are a challenge to standard approaches to emulation, such as a long run-time, multivariate output, periodicity, and strong constraints on the inter-relationship between inputs and outputs. These kinds of features are not unusual in models of complex systems. We show how they can be handled in an emulator, and demonstrat...