This year marks the 50th anniversary of Crick's seminal paper on the packing of alpha-helices into coiled-coil structures. The central tenet of Crick's work is the interdigitation of side chains, which directs the helix-helix interactions; so called knobs-into-holes packing. Subsequent determinations of coiled-coil-protein sequences and structures confirmed the key features of Crick's model and...

Sellers in social marketplaces actively engage following behaviors. However, extant research has repeatedly reported a negative effect of the followee number on seller performance, raising questions about sellers’ value others. Intrigued by this question, study applies theory structural holes to understand and explain following. That is, sellers whose networks span more are better positioned ga...

This work investigates a Fano filter design based on nano-hole array, patterned in fused silica using high-energy ultrafast femtosecond laser pulses. After carefully observing the experimental results, structural profile of nano-holes is numerically modeled 3D finite-difference time-domain-based software platform. The metasurface consists conical shaped air holes structured substrate, and later...

We presented a case of full-thickness macular hole progressing into lamellar macular hole as seen in the spectral domain optical coherence tomography. Short review of the literature regarding the pathogenesis of lamellar hole was presented and discussed.

Virus capsids are highly specific assemblies that are formed from a large number of often chemically identical capsid subunits. In the present paper we ask to what extent these structures can be viewed as mathematically tilable objects using a single two-dimensional tile. We find that spherical viruses from a large number of families-eight out of the twelve studied-qualitatively possess propert...

evaluated under laboratory condition. the objective of the present study was to observe the effect of impregnated torn bednets on the number of bites by an. culicifacies a glass made tunnel test was designed to the effect of torn bednets treated with three dosages of cyfluthrin 5% ew, were induce hungry female mosquitoes to pass through holes cut in the pyrethroid treated nets. a guinea pig use...

Aerospace and aircraft companies follow a pyramidal structure of testing, ranging from specimen tests to full-scale tests, for structural design. At the base level, open hole strength evaluation is one qualification procedures composite components. The holes are made in components accommodate bolts rivets order assemble parts into single unit. Holes component also used fulfill functional requir...

The responsibility of a Structural Engineer lies in not merely designing the structure based on safety and serviceability considerations but he also has to consider the functional requirements based on the use to which the structure is intended. While designing a power plant structure or a multi-storeyed building, the traditional structural steel framing consists of beams and girders with solid...