Recently, we proposed a hierarchical model for the elastic properties of mineralized lobster cuticle using (i) ab initio calculations for the chitin properties and (ii) hierarchical homogenization performed in a bottom-up order through all length scales. It has been found that the cuticle possesses nearly extremal, excellent mechanical properties in terms of stiffness that strongly depend on th...

The structural risk of West Nile Disease results from the usual functioning of the socio-ecological system, which may favour the introduction of the pathogen, its circulation and the occurrence of disease cases. Its geographic variations result from the local interactions between three components: (i) reservoir hosts, (ii) vectors, both characterized by their diversity, abundance and competence...

nanocrystalline zno particles were prepared by a novel sonochemical route from zinc acetate and sodium hydroxide without any requirement of calcination steps at high temperature and without surfactants. variations in several parameters and their effects on the structural (crystal size and morphology) properties of nanoparticles were investigated. characterizations were carried out by x-ray diff...

Knowledge of spatial chromosomal organizations is critical for the study of transcriptional regulation and other nuclear processes in the cell. Recently, chromosome conformation capture (3C) based technologies, such as Hi-C and TCC, have been developed to provide a genome-wide, three-dimensional (3D) view of chromatin organization. Appropriate methods for analyzing these data and fully characte...

Warping can be used to reduce interindividual structural variations of threedimensional anatomical image datasets of brains. For this, a standard brain is generated and the individual datasets are matched to this reference system. Model-based warping uses structural information such as landmarks to construct the spatial correspondence between the datasets. In this paper we compare three differe...

This dissertation focuses on the problem of wing planform optimization for transonic aircraft based on flow simulation using Computational Fluid Dynamics(CFD) combined with an adjoint-gradient based numerical optimization procedure. The adjoint method, traditionally used for wing section design has been extended to cover planform variations and to compute the sensitivities of the structural wei...

Brain networks are becoming forefront research in neuroscience. Network-based analysis on the functional and structural connectomes can lead to powerful imaging markers for brain diseases. However, constructing the structural connectome can be based upon different acquisition and reconstruction techniques whose information content and mutual differences has not yet been properly studied in a un...

In addition to single-nucleotide polymorphisms, structural variation is abundant in many plant genomes. The structural variation across a species can be represented by a 'pan-genome', which is essential to fully understand the genetic control of phenotypes. However, the pan-genome's complexity hinders its accurate assembly via sequence alignment. Here we demonstrate an approach to facilitate pa...