Objective To describe the clinical presentation, magnetic resonance imaging (MRI) findings, and outcome of dogs treated surgically for lumbosacral intervertebral disk extrusion (IVDE). Study Design Retrospective study. Animals Thirteen dogs. Methods Records MRI studies with intraoperatively confirmed IVDE were reviewed. features thoracolumbar applied to all cases. Postoperative was subjectively...

The current study investigated the toxicity of ethanol extract _Olea africana_ in mice and brine shrimp _(Artemia salina)_. Brine cytotoxicity acute were observed over 24 hours. Subacute was studied for 28 days using animal weight, organ-to-body weight ratio, hematological, biochemical histological parameters as indicators. Data analysis done Probit regression Two Way ANOVA _(p<0.05)_. letha...

CONTEXT Copper deficiency myelopathy represents an often underdiagnosed, acquired neurological syndrome, clinically characterized by posterior column dysfunction. The main causes of copper deficiency are bariatric surgery, increased consumption of zinc, and malabsorption. However, even after a careful history taking and extensive laboratory researches, the etiology of copper deficiency remains ...

To date nothing is known about the subacute phase of neurodegeneration following injury in invertebrates. Among few clues available are the results published by our group reporting hemocytes and activated glial cells at chronic and acute phases of the lesion. In vertebrates, glial activation and recruitment of immunological cells are crucial events during neurodegeneration. Here, we aimed to st...

A 29-year-old woman with relapsed T-cell acute lymphoblastic leukemia presented 4 months of progressive ataxia, weakness, and bowel/bladder incontinence. Symptoms started after completing 2 cycles nelarabine. Examination revealed paraplegia complete sensory loss from mid-chest down, vibration joint position in upper limbs, areflexia, bilateral Babinski signs. EMG showed fibrillation potentials ...

The complex morphology of axons presents a challenge in understanding axonal responses to injury and disease. By in vivo two-photon imaging of spinal dorsal column sensory axons, we systematically examined the effect of injury location relative to the main bifurcation point on axon degeneration and regeneration following highly localized laser injuries. Retrograde but not anterograde degenerati...

The gross and histopathological lesions of 10 cases in a natural outbreak of aflatoxicosis amongst dogs in the Republic of South Africa are reported. The 10 cases were classified as acute (1 case), subacute (7 cases) and chronic (2 cases) on the basis of the nature, degree and extent of the following histopathological fractures: hepatocellular fatty degeneration, necrosis or regeneration; proli...

We describe a 20-year-old man with Smith-Magenis syndrome and a 46,XY,del(17)(p11.2p11.2) karyotype. The interstitial deletion was confirmed by metaphase analysis using the fluorescent in situ hybridization probe (D17S29) for the Smith-Magenis region. The patient had hypertelorism, exotropia, and high myopia. Examination under anesthesia showed a lacquer crack near the right macula and a discif...

Background: Subacute and chronic subdural haematoma is a common problem in the elderly population. It occurs in the context of cerebral degeneration. Trauma, intracranial hypotension, coagulopathy and chronic alcoholism are also predisposing factors. Clinical profile may present similarly to stroke, raised intracranial pressure (ICP) or dementia. CT and MRI are the diagnostic investigations. Bu...

SCD(Subacute combined degeneration) also known as Lichtheim's disease, refers to degeneration of the posterior and lateral columns of the spinal cord due to various causes vitamin B12 deficiency (most common), copper deficiency or vitamin E deficiency. The clinical manifestation of this entity lagging behind spinal Magnetic resonance (MR) imaging, demands MRI to be used as a screening tool. How...