A diverse collection of 123 meningococcal and 126 gonococcal isolates was tested for susceptibility to N-formimidoyl thienamycin (N-F-thienamycin; MK0787) and to penicillin G (PEN). All of the meningococci were susceptible to both of these, as well as to rifampin. Among gonococci, beta-lactamase-producing strains, which were resistant to PEN, were susceptible to N-F-thienamycin. Among non-beta-...

The aminoglycosides paromomycin and neomycin were examined in Escherichia coli cells for an inhibitory effect on 30S ribosomal subunit assembly. Both compounds inhibited the growth rate, viable cell number, and protein synthesis rate with similar 50% inhibitory concentrations. Each drug also showed a concentration-dependent inhibition of 30S subunit formation. The inhibitory effect on 30S parti...

Objective: Infections are increasing caused by antibiotic-resistant Pseudomonas aeruginosa day by day. For this reason, many researchers have tried to find new compounds as alternative antibiotics. The purpose of this study was to evaluate the effect of yarrow extract, green tea and Ajowan  on Pseudomonas aeruginosa. Methods: Extraction  of Achillea, green tea and Ajowan was done with rotary. F...