نتایج جستجو برای: succinate dehydrogenase
تعداد نتایج: 75966 فیلتر نتایج به سال:
In oxygen-deprived heart muscle tissue, alanine levels increase, whereas levels of glutamate and aspartate decline, and it is therefore postulated that free tissue amino acids participate in the metabolic response to cardiac hypoxia. Succinate is a hypothetical end product of anaerobic metabolism of glutamate and aspartate. To test this hypothesis in vitro isolated right ventricular papillary m...
3-BrPA (3-bromopyruvate) is an alkylating agent with anti-tumoral activity on hepatocellular carcinoma. This compound inhibits cellular ATP production owing to its action on glycolysis and oxidative phosphorylation; however, the specific metabolic steps and mechanisms of 3-BrPA action in human hepatocellular carcinomas, particularly its effects on mitochondrial energetics, are poorly understood...
Mammalian succinate dehydrogenase exists in unactivated and activated states. Transition of the unactivated enzyme to the activated form appears to be a conformation change initiated by combination of the protein with substrates or competitive inhibitors and results in a many-fold increase in catalytic activity. This activation has now been shown to be reversible on removal of the bound activat...
Objective: The aim of the study was to analyze a series of Brazilian patients suffering from MELAS. Method: Ten patients with MELAS were studied with correlation between clinical findings, laboratorial data, electrophysiology, histochemical and molecular features. Results: Blood lactate was increased in eight patients. Brain image studies revealed a stroke-like pattern in all patients. Muscle b...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید