A substantial literature describes the capacity of all addictive drugs to slow cell growth and potentiate apoptosis. Flow cytometry was used as a means to compare two lineages of circulating progenitor cells in addicted patients. Buprenorphine treated opiate addicts were compared with medical patients. Peripheral venous blood CD34(+) CD45(+) double positive cells were counted as haemopoietic st...

Introduction Attention-deficit/hyperactivity disorder (ADHD) is a common comorbid disorder in patients suffering from substance use disorder (SUD). Individuals with co-occurring SUD and ADHD are more likely than SUD patients without ADHD to have developed SUD at a younger age, be polysubstance users, and need inpatient treatment more often. The present study investigates whether individuals wit...

BACKGROUND Adolescents with attention-deficit/hyperactivity disorder (ADHD) are known to be at significantly greater risk for the development of substance use disorders (SUD) compared to peers. Impulsivity, which could lead to higher levels of drug use, is a known symptom of ADHD and likely accounts, in part, for this relationship. Other factors, such as a biologically increased susceptibility ...

OBJECTIVE The main aim of this study was to use familial risk analysis to examine the association between attention deficit hyperactivity disorder (ADHD) and substance use disorders (SUDs) attending to sex effects and the specificity of alcohol and drug use disorder risks. METHODS Subjects were derived from two longitudinal case-control family studies of probands aged 6-17 years with and with...

The present paper studies the symmetries of the Hubbard model of electrons with generally n-fold orbital degeneracy. It is shown that SUd(2n) and SUc(2n) symmetries hold, respectively, for the model with completely repulsive or attractive on-site interaction and that with partly attractive interactions. An extended Lieb– Mattis transformation is given to map these two symmetries into each other...

BACKGROUND Traumatic experiences and, more specifically, posttraumatic stress disorder (PTSD) are highly prevalent among substance use disorder (SUD) patients. This comorbidity is associated with worse treatment outcomes in substance use treatment programs and more crisis interventions. International guidelines advise an integrated approach to the treatment of trauma related problems and SUD. S...

OBJECTIVE Concerns exist that stimulant therapy of youths with attention-deficit/hyperactivity disorder (ADHD) may result in an increased risk for subsequent substance use disorders (SUD). We investigated all long-term studies in which pharmacologically treated and untreated youths with ADHD were examined for later SUD outcomes. METHODS A search of all available prospective and retrospective ...

Introduction People with mental disorders may present impairments in cognitive and metacognitive functions. Self-reflection is the ability to reflect on oneself (specifically one’s behavior, emotions, thoughts) insight awareness of internal experience. Mindwandering (MW) defined as tendency divert attention from current reality without a clearly intention. It can be spontaneous or deliberate. S...

Présentée et soutenue publiquement le 24 novembre 2011 Jury Rapporteurs : Prof. Mohand-Said Hacid, Université Claude Bernard Lyon 1, France Prof. Paola Inverardi, Università degli Studi dell’Aquila, Italy Prof. Fabrice Kordon, Université Pierre et Marie Curie Paris 6, France Examinateurs : Prof. Philippe Dague, Université Paris Sud, France Prof. Marie-Claude Gaudel, Université Paris Sud, France...

J. P. Gauyacq1,* and N. Lorente2 1Institut des Sciences Moléculaires d’Orsay, ISMO, Unité mixte de recherches CNRS-Université Paris-Sud, UMR 8214, Bâtiment 351, Université Paris-Sud, 91405 Orsay Cedex, France 2Centre d’Investigació en Nanociéncia i Nanotecnologia (CSIC-ICN), Campus de la UAB, E-08193 Bellaterra, Spain (Received 21 September 2011; revised manuscript received 27 December 2011; pu...