BACKGROUND Zygomycosis is a difficult to treat and frequently fatal infection affecting immunocompromised and (rarely) immunocompetent patients. It requires a multifaceted approach involving elimination of predisposing factors, surgical debridement, and antifungal therapy. CASE REPORT We report the case of a postrenal transplant patient who developed disseminated zygomycosis with vascular ane...

The first ever published Guidelines on Antithrombotic therapy in vascular surgical patients, is the highlight of this issue. Although previous guidelines PAD, ALI, carotid artery disease, AAA, etc, have included recommendations antithrombotic therapy, many our patients multiple lesions. For time, a multidisciplinary writing committee has merged data all these fields, must read!

Introduction Hereditary hemorrhagic telangiectasia (HHT, M. Osler) is an autosomal-dominant hereditary disease that can lead to the development of arteriovenous malformation and skin mucous membranes. The leading symptom epistaxis, severity which vary greatly from patient patient. Therapy only symptomatically oriented. In addition surgical medicinal therapy approaches, adequate care nasal mucos...

Esophageal cancer is one of the most aggressive malignancies gastrointestinal tract, characterized by high malignancy potential and poor prognosis. Surgical treatment standard for localized esophageal cancer, but results only surgery locally advanced tumors remain unsatisfactory. The use neoadjuvant chemotherapy, as well chemoradiation therapy, leads to a downstaging tumor, improves its resecta...

This article reports non-surgical endodontic retreatment of two patients with persistent or recurrent periapical lesions, who had previously undergone surgical and non-surgical endodontic therapy respectively. It further discusses and reviews the relevance of classification of periapical lesions, the explanation behind healing of periapical lesions by endodontic therapy alone, causes of persist...

OBJECTIVE To systematically review the evidence of effectiveness of surgical vs. non-surgical therapy for the treatment of chronic periodontal disease. METHODS A search was conducted for randomized controlled trials of at least 12 months duration comparing surgical with non-surgical treatment of chronic periodontal disease. Data sources included the National Library of Medicine computerised b...

OBJECTIVES National and international evidence-based guidelines for hip and knee osteoarthritis (OA) recommend to start with non-surgical treatments, followed by surgical intervention if a patient does not respond sufficiently to non-surgical treatments, but there are indications that these are not optimally used. The aim of this study was to assess the extent to which all recommended non-surgi...

Standard therapy for glioblastoma (GBM) includes maximal surgical resection and radiation therapy. While it is established that radiation therapy provides the greatest survival benefit of standard treatment modalities, the impact of the extent of surgical resection (EOR) on patient outcome remains highly controversial. While some studies describe no correlation between EOR and patient survival ...