نتایج جستجو برای: sustained virological responses

تعداد نتایج: 476190  

2014
Hiroshi Abe Akihito Tsubota Noritomo Shimada Masanori Atsukawa Keizo Kato Koichi Takaguchi Toru Asano Yoshimichi Chuganji Choitsu Sakamoto Hidenori Toyoda Takashi Kumada Tatsuya Ide Michio Sata Yoshio Aizawa

We evaluated the genetic variation in rs8099917, substitutions in core amino acid (aa) 70, and the number of aa substitutions in the interferon sensitivity-determining region (ISDR) on the prediction of sustained virological response (SVR) in treatment-naïve hepatitis C virus (HCV) genotype 1b (G1b) patients. This multicenter study involved 150 Asian treatment-naïve patients infected with HCV G...

2014
Hongbo Chen Yuanyuan Zhang Peng Huang Yin Xu Jie Wang Jing Su Rongbin Yu

Previous studies have suggested that host genetic polymorphisms may affect virological response to pegylated-interferon and ribavirin (PEG-IFN/ ribavirin) therapy in chronic HCV infection. IL28B and MxA are the most intensively studied genes in Chinese Han population. The current research is to summarize published data and evaluate the overall association of meaningful SNPs in these two genes w...

Journal: :hepatitis monthly 0
saeedeh ravi department of clinical pharmacy, faculty of pharmacy, tehran university of medical sciences, tehran, ir iran; department of clinical pharmacy, pharmaceutical sciences branch, islamic azad university,, tehran, ir iran mohsen nasiri toosi department of gastroenterology, faculty of medicine, tehran university of medical sciences, tehran, ir iran iman karimzadeh department of clinical pharmacy, faculty of pharmacy, tehran university of medical sciences, tehran, ir iran mehdi ahadi-barzoki department of clinical pharmacy, faculty of pharmacy, zanjan university of medical sciences, zanjan, ir iran hossein khalili department of clinical pharmacy, faculty of pharmacy, tehran university of medical sciences, tehran, ir iran; department of clinical pharmacy, faculty of pharmacy, tehran university of medical sciences, p.o. box: 14155/6451, tehran, ir iran. tel: +98-9122979329, fax: +98-2166461178

background various aspects of adherence to hcv treatment such as frequency, risk factors as well as causes of non-adherence, and its real role in clinical and virological outcome of the infected patients have remained largely unknown. objectives the current study aimed to evaluate patients’ adherence to anti-hcv medications in iran. materials and methods from october 2010 to march 2011, socio-d...

Journal: :hepatitis monthly 0
bita behnava iran hepatitis network, tehran, ir iran; baqiyatallah research center for gastroenterology and liver diseases, baqiyatallah university of medical sciences, tehran, ir iran; middle east liver diseases (meld) center, tehran, ir iran heidar sharafi iran hepatitis network, tehran, ir iran; baqiyatallah research center for gastroenterology and liver diseases, baqiyatallah university of medical sciences, tehran, ir iran; middle east liver diseases (meld) center, tehran, ir iran; armin pathobiology laboratory, tehran, ir iran maryam keshvari iran hepatitis network, tehran, ir iran; blood transfusion research center, high institute for research and education in transfusion medicine, tehran, ir iran ali pouryasin iran hepatitis network, tehran, ir iran; armin pathobiology laboratory, tehran, ir iran; department of biology, arsanjan branch, islamic azad university, arsanjan, ir iran leila mehrnoush iran hepatitis network, tehran, ir iran; middle east liver diseases (meld) center, tehran, ir iran shima salimi iran hepatitis network, tehran, ir iran; middle east liver diseases (meld) center, tehran, ir iran

patients and methods this cross - sectional study was conducted on 143 thalassemic patients with chronic hepatitis c, who were treated with a combination of peg-ifn and rbv regimen. the rs12979860 and rs8099917 polymorphisms were assessed as the most common polymorphisms near the il28b gene by the polymerase chain reaction-restriction fragment length polymorphism (pcr-rflp) method. objectives w...

Journal: :acta medica iranica 0
f.farokhy m. mahmoudian s. gerayesh-nejad a. r. dehpour

- verapamil produces a sustained contraction in isolated biventer-cervicis muscle of chickens between 2-8 days old. from cumulative dose-response curves, ed50 of was calculated for this effect of verapamil. when isolated chicken biventer-cervicis muscle was electrically stimulated, verapamil had no effect on twitch contractures but increased the base line tone of the muscle. glycerol treatment ...

Journal: :Gut 2002
C Cammà S Bruno F Schepis O Lo Iacono P Andreone A G Gramenzi A Mangia A Andriulli M Puoti A Spadaro M Freni V Di Marco L Cino G Saracco A Chiesa A Crosignani N Caporaso F Morisco M G Rumi A Craxì

BACKGROUND AND AIMS Retreatment with a combination of alpha interferon (IFN) plus ribavirin of patients with chronic hepatitis C who did not respond to IFN monotherapy has not been assessed in large controlled studies. METHODS To assess the effectiveness and tolerability of IFN/ribavirin retreatment of non-responders to IFN and to identify predictors of complete (biochemical and virological) ...

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