Background: Septilin (Spt) is an ayurvedic drug formulation from Himalaya Drug Company and is well-known for its antibacterial, anti-inflammatory and immunomodulatory activities. Interest in the use of medicinal plants and herbal medicine as immunomodulators has currently been the subject of scientific investigation worldwide. Cyclophosphamide (CP) and Cisplatin (Csp) are widely used chemothera...

The harmful effect of electromagnetic radiations emitted from VDU (video display unit) on red blood cells of Swiss albino mice, 20 cm away, at power density of 0.295 w/cm was investigated, at the interval of 7, 14, 28, 42 and 56days. The result showed altered blood smear, morphology and scanning electron micrograph of RBCs. red blood cell count, hemoglobin concentration was reduced up to day 4...

The etiological agent of the acute hepatitis encountered in weanling mice of the Princeton strain is a virus found in the liver, spleen, kidneys, heart's blood, urine, and intestinal contents of experimentally infected animals. Older Princeton mice and weanlings from four other strains (Swiss, Webster's BSVS, C albino) and Bagg) proved to be less susceptible than Princeton weanlings. The virus ...

The crude ethanol extract of the stem Tinospora cordifolia (Family Menispermaceae) was evaluated for its antioxidant and analgesic activities. property T. assessed by 1, 1-diphenyl –2- picryl hydrazyl (DPPH) free radical scavenging assay. showed potential activity (IC50 about 52.80 µg/ml), which comparable to standard drug ascorbic acid 4.12 µg ml-1). ethanolic also exhibited statistically sign...

Exosomes are nanoparticles (carriers) that play vital role in intercellular communication of cells. The present study was aimed at investigating exosomes isolated from biological fluids for their biological applications in disease treatment especially as analgesic drug carrier. Exosomes were isolated from the kidney of cattle through ultracentrifugation of blood, and characterized by inverted s...

Objectives: This work aimed to evaluate the acute and chronic toxicity of ethanolic extract Abelmoschus esculentus, administered orally Swiss albino mice. Methods: An dosage 2000 mg/kg was administrated studies were conducted following organization for economic cooperation development guidelines 425 407 respectively in During study, general signs monitored. The mice which are used toxicology st...

genistein is a soya isoflavone, which is found naturally in legumes, such as soybeans and chickpeas. the intraperitoneal administration of the optimum dose (200 mg/kg) of genistein 24 h and 15 minbefore irradiation (8 gy at a dose rate of 1.02 gy/min) recovered the deficit in protein content (28.63±1.44%) and the dna content (21.61±8.19%) if an average of 5 intervals of autopsies 1st, 3rd, 7th,...

Introduction: The morphology of endometrium undergoes changes in response to the sex hormones periodically. Estrogen predominantly causes mitotic activity and increases the proliferation of endometrium and progesterone antagonizes the activity of estrogen. However, factors which increase the circulating levels of estrogens such as exogenous intake of hormonal pills or endogenous increase of est...

OBJECTIVE To investigate the effect of octreotide, a long-acting analogue of somatostatin, on postoperative adhesion formation, because somatostatin inhibits secretion of some growth factors that have modulatory effects on collagen synthesis. DESIGN An experimental study. SETTING Surgical Research and Biochemistry laboratories at Hacettepe University, Ankara, Turkey. SUBJECTS Male Swiss a...

Antiallergic activity of Aristolochia bracteolata was evaluated by using compound 48/80 induced anaphylaxis, dermatitis rhinitis and pruritus, as a preclinical model for acute phase of hypersensitivity reactions. The late phase hypersensitivity was evidenced by considering toluidine diisocyanate induced volume of bronchoalveolar fluid secretion and its inhibition. The possible antiallergic mech...