Dosage for the galvanic stimulation for iontophoresis varies. Clinicians manipulate the duration or the amplitude of the current, but it is not known which is more effective. We compared the anesthetic effect of lidocaine HCL (2%) by manipulating the current parameters on 21 healthy volunteers (age: 21.2 ± 4.2, height 170.7 ± 10.2 cm, mass 82.1 ± 19.2 kg). Three conditions were administered in ...

Mutations of the fragile X mental retardation 1 (FMR1) gene are the genetic cause of fragile X syndrome (FXS). Large expansions of the CGG repeat (>200 repeats) consequently result in transcriptional silencing of the FMR1 gene and deficiency/absence of the FMR1 protein (FMRP). Carriers with a premutation allele (55-200 of CGG repeats) are often associated with mildly reduced levels of FMRP and/...

Onset of south west monsoon (SWM) over Kerala is associated with intense convection followed by heavy rainfall the west-coast India. The events are usually meso-scale convective systems embedded in large scale synoptic system Arabian Sea. Such deep and cumulus can have an important effect on dynamics energetics large-scale atmospheric systems, because magnitudes energy transformations changes p...

Climate projections have confirmed the need to adapt a changing climate, but been less beneficial in guiding how effectively adapt. The reason is uncertainty cascade, from assumptions about future emissions of greenhouse gases what that means for climate real decisions on local scale. Each steps process contains and these uncertainties various levels assessment accumulate. This cascade should b...

We consider profit-maximization problems for combinatorial auctions with non-single minded valuation functions and limited supply. We obtain fairly general results that relate the approximability of the profit-maximization problem to that of the corresponding social-welfare-maximization (SWM) problem, which is the problem of finding an allocation (S1, . . . , Sn) satisfying the capacity constra...

The economic growth and demographic changes in Indian cities are posing a serious challenge to urban local authorities. By the year 2020, Indian urban centers including Bangalore will witness a huge increase in population. With the rapidly growing urban population, the need for infrastructure services increases manifold. The increase in per capita income and the concomitant industrial and servi...

Like most developing countries, Zambia has been going through very difficult times economically. This has seriously affected the capacity of various government agencies to provide public services. As a result the government and its agencies have over the past decade been forced to reassess the way in which publicly provided urban services are delivered. The key policy response has been a moveme...