Systemic mastocytosis with associated clonal hematologic non-mast cell lineage disease (SMAHNMD) is a subtype of systemic mastocytosis (SM) characterized by neoplastic proliferation of mast cells in association with a hematologic neoplasm defined by the World Health Organization (WHO) criteria. SM-AHNMD is more commonly associated with myeloid neoplasms such as, chronic myelomonocytic leukemia ...

Mast cell leukemia (MCL) is a very rare form of aggressive systemic mastocytosis accounting for < 1% all mastocytosis. Mastocytosis broad term used group clonal disorders characterized by accumulation mast cells in the skin with or without extracutaneous involvement. The clinical spectrum disease varies from only cutaneous lesions to highly involvement such as MCL. can present birth adulthoo...

Background Mastocytosis is a neoplastic condition characterized by the accumulation of mast cells (MCs) in 1 or more organ. Adults tend to have persistent, systemic mastocytosis, whereas MC infiltration children usually limited skin and typically regresses after several years. Both adults could display cell activation symptoms (MCASs) due mediator release. In than 85% both adult pediatric cases...

In systemic mastocytosis (SM), the clinical features and survival vary greatly. Patient-related factors determining outcome in SM are largely unknown. Methods: We examined impact of sex on features, progression-free (PFS), overall (OS) 3403 patients with collected registry European Competence Network Mastocytosis (ECNM). The cytogenetic molecular genetic aberrations differences was analyzed a s...

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Feminist standpoint theory has a contentious history. It is an explicitly political as well as social epistemology, characterized by the thesis that those who are marginalized or oppressed under conditions of systemic inequity may, in fact, be better knowers, in a number of respects, than those who are socially or economically privileged. Their epistemic advantage arises from the kinds of exper...