نتایج جستجو برای: t1
تعداد نتایج: 33331 فیلتر نتایج به سال:
PURPOSE To explore the use and reproducibility of magnetic resonance-derived myocardial T1 mapping in patients with iron overload. MATERIALS AND METHODS The research received ethics committee approval and all patients provided written informed consent. This was a prospective study of 88 patients and 67 healthy volunteers. Thirty-five patients underwent repeat scanning for reproducibility. T1 ...
PURPOSE Interest in using T1 as a potential MRI biomarker of chronic obstructive pulmonary disease (COPD) has recently increased. Since tobacco smoking is the major risk factor for development of COPD, the aim for this study was to examine whether tobacco smoking, pack-years (PY), influenced T1 of the lung parenchyma in asymptomatic current smokers. MATERIALS AND METHODS Lung T1 measurements ...
OBJECTIVE This study aimed to compare the diagnostic performance in the detection of brain metastases between contrast-enhanced T1-weighted volume isotropic turbo spin echo acquisition (T1-VISTA) and 3-dimensional T1-weighted fluid-attenuated inversion recovery (3D-T1-FLAIR) imaging at 3 T. METHODS Two neuroradiologists selected 129 true (metastases) and 70 false (vessels and artifacts) lesio...
OBJECTIVE Neuromelanin loss of substantia nigra (SN) can be visualized as a T1 signal reduction on T1-weighted high-resolution imaging. We investigated whether volumetric analysis of T1 hyperintensity for SN could be used to differentiate between Parkinson's disease dementia (PDD), Alzheimer's disease (AD) and age-matched controls. MATERIALS AND METHODS This retrospective study enrolled 10 pa...
OBJECTIVE For extended-release drugs with multi-compartment kinetics, such as topiramate, effective half-life (t1/2eff) may be a more clinically relevant parameter than elimination half-life (t1/2z). Using topiramate as a real-life example, the objective was to compare these half-life values for immediate- and extended-release topiramate (TPM-IR and USL255, respectively) to understand how drug ...
BACKGROUND Myocardial fibrosis is linked with adverse clinical outcomes in adults after tetralogy of Fallot repair (rTOF). Native T1 times (T1) by cardiac magnetic resonance have been shown to be a surrogate marker of diffuse myocardial fibrosis. The objective was to quantify native T1 in children post-rTOF and to evaluate their relationship with surgical, imaging, and clinical factors. METHO...
BACKGROUND Myocardial black blood (BB) T2* relaxometry at 1.5T provides robust, reproducible and calibrated non-invasive assessment of cardiac iron burden. In vitro data has shown that like T2*, novel native Modified Look-Locker Inversion recovery (MOLLI) T1 shortens with increasing tissue iron. The relative merits of T1 and T2* are largely unexplored. We compared the established 1.5T BB T2* te...
– The module extraction problem: given a terminology T1 and a signature Σ, extract from T1 a minimal self-contained terminology T0 such that T1 and T0 imply the same dependencies between Σ-terms. – The logical diff problem: given a signature Σ and two versions T0 and T1 of a terminology, check whether T0 and T1 are logically different in the sense that they do not imply the same dependencies be...
Background T1-mapping, directly measuring the underlying longitudinal relaxation times (T1), and extracellular volume (ECV) quantification, are emerging techniques for myocardial fibrosis quantification. Recent studies have reported significant T1 differences in fibrotic and normal tissue, but whole-heart T1-mapping is rarely performed in clinical practice, due to the associated time-consuming ...
We present an algorithm which, given a hypergeometric term T (n), constructs hypergeometric terms T1(n) and T2(n) such that T (n) = T1(n + 1) ? T1(n) + T2(n), and T2(n) is minimal in some sense. This solves the decomposition problem for indeenite sums of hypergeometric terms: T1(n + 1) ? T1(n) is the \summable part" and T2(n) the \non-summable part" of T (n).
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