The chemokine receptor CXCR3 is involved in various inflammatory diseases, such as rheumatoid arthritis, multiple sclerosis, psoriasis, and allograft rejection in transplantation patients. The CXCR3 ligands CXCL9, CXCL10, and CXCL11 are expressed at sites of inflammation, and they attract CXCR3-bearing lymphocytes, thus contributing to the inflammatory process. In this study, we characterize fi...

Ekolojik sistem anlam?nda bir k?saltma olarak dilimizde yer eden ekosistem, çevrecilik ile ilgili kavramd?r. Do?an?n sahip oldu?u düzeni tan?mlar. Bu düzen, herhangi müdahale olmadan, do?an?n kendi i?leyi?idir. Egosistem tabirindeki ego kelimesi ise Türk Dil Kurumuna göre do?rudan “ben” anlam?na gelmektedir. Endüstriyel üretimlerde çevreci yakla??mlardan uzak, bilinçsiz tahribat söz konusu gibi...

Pojęcie zmiennej losowej jest tak stare, jak sam rachunek prawdopodobieństwa. Ten dział matematyki został zapoczątkowany w XVII stuleciu, zaś impulsem do jego powstania było obliczanie prawdopodobieństwa wystąpienia róŜnych konfiguracji przy grze w kości. A1. Pojęcie zmiennej losowej Wynik rzutu kostką stanowi przykład zmiennej losowej dyskretnej. Liczby naturalne: 1, 2, 3, 4, 5 i 6 występują z...

A match statistic considered by Khidr (1981) is interpreted in terms of crossings of the empirical and true distribution functions and a simpler alternate derivation of its distribution provided. This approach can also be used to obtain the distribution of a two-sample match statistic, considered earlier by Tak~tcs (1971).

Discussiot and(Corresponden-ce: Einistein, Displacemenit oni the Plates tak-ent at the Aiustraliant Eclipse: DR. C. A. CHANT. Fiundamental Classificationi of Galls: DR. B. W. WELLS. Athletics anid the Americat Association. for the Advanmcement of Scieuce: PROFESSOR H. M. PARSHLEY. IfWar Explosives mistaken fOr' Minerls: PROFESSOR F. N. GUILD. Biological Inistitutes inl Russia: PROFESSOR H. J. A...

BACKGROUND In Tak province, Thailand migrants and refugees from Myanmar navigate a pluralistic healthcare system to seek Tuberculosis (TB) care from a variety of government and non-governmental providers. This multi-methods qualitative study examined access to TB, TB/HIV and multidrug-resistant tuberculosis (MDR-TB) treatment with an emphasis on barriers to care and enabling factors. METHODS ...

Sepsis is one of the leading causes of mortality in severe systemic inflammatory syndrome. The endotoxin-induced inflammatory response has been linked to the development of sepsis. Rhein is a lipophilic anthraquinone isolated from Rheum rhabarbarum (rhubarb), which has a protective effect on intestinal damage in vivo. However, the underlying mechanism responsible for the protective effects of r...

BACKGROUND This study was conducted to investigate the role of toll-like receptor 4 (TLR4) in mediating acute kidney injury in endotoxemic sheep using the selective TLR4 inhibitor TAK-242. METHODS A randomized, controlled, experimental study was performed with 20 adult Texel crossbred sheep. Before an Escherichia coli lipopolysaccharide infusion (3 μg · kg(-1) · h(-1) for 24 h), sheep were ra...