Tocopherol-associated protein (TAP) was expressed in mouse mast cells. TAP was predominantly localized in the cytoplasm, and the subcellular localization was not changed by alpha-tocopherol. The results suggest that the physiological role of TAP in mast cells is not regulation of tocopherol function but an as-yet-unidentified activity.

BACKGROUND Water-related diseases are of great concern in developing countries like Nepal. Every year, there are countless morbidity and mortality due to the consumption of unsafe drinking water. Recently, there have been increased uses of bottled drinking water in an assumption that the bottled water is safer than the tap water and its use will help to protect from water-related diseases. So, ...

We study the demand for household water connections in urban Morocco, and the effect of such connections on household welfare. In the northern city of Tangiers, among homeowners without a private connection to the city’s water grid, a random subset was offered a simplified procedure to purchase a household connection on credit (at a zero percent interest rate). Take-up was high, at 69%. Because...

The control used for the tapchanger of an LTC transformer or step-voltage regulator is a prime illustration of electronic technology advances applied to the power industry. Electro-mechanical (balance-beam and induction disc), discrete static, integrated circuit static and now digital designs have evolved over the past forty years. This increased product sophistication has made possible many fe...

Abstract We recommend a flexible channel propagation model, which includes no more than three taps and has flexible tap gains and tap delays. The tap gains have a progressive decrease relationship, while the tap delays have a progressive increase one. The model is valid under the following assumptions: (1) there is line-of-sight propagation, (2) highly directional antennas are used at least at ...

The power of an adaptive equalizer is maximized when the structural parameters including the tap-length and decision delay can be optimally chosen. Although the method for adjusting either the tap-length or decision delay has been proposed, adjusting both simultaneously becomes much more involved as they interact with each other. In this paper, this problem is solved by putting a linear prewhit...

In 2013, an oropharyngeal tularemia outbreak in Turkey affected 55 persons. Drinking tap water during the likely exposure period was significantly associated with illness (attack rate 27% vs. 11% among non-tap water drinkers). Findings showed the tap water source had been contaminated by surface water, and the chlorination device malfunctioned.

Background: The transporter associated with antigen processing (TAP) is an ABC transporter whose experimental structure is not known. Results:We have modeled TAP based on the crystal structures of three related ABC transporters. Conclusion:We identified a possible peptide binding conformation in the transport cycle of TAP. Significance:These models help interpret experimental data and give info...

Peripheral blood natural killer (NK) cells from patients with transporter associated with antigen processing (TAP) deficiency are hyporesponsive. The mechanism of this defect is unknown, but the phenotype of TAP-deficient NK cells is almost normal. However, we noticed a high percentage of CD56(bright) cells among total NK cells from two patients. We further investigated TAP-deficient NK cells i...