Saliva plays major roles in the human-to-human transmission of SARS-CoV-2. If virus saliva SARS-CoV-2-infected individuals can be rapidly and efficiently inactivated by a beverage, ingestion beverage may attenuate spread infection within population. Recently, we reported that SARS-CoV-2 was significantly treatment with black tea, green roasted tea oolong as well their constituents, (-) epigallo...

UNLABELLED Mengovirus, a member of thePicornaviridaefamily, has a broad cell tropism and can cause encephalitis and myocarditis in multiple mammalian species. Attenuation has been achieved by shortening the polycytidine tract in the 5' noncoding region (NCR). A poly(C)-truncated strain of mengovirus, vMC24, resulted in significant tumor regression in immunocompetent BALB/c mice bearing syngenei...

Reactive changes occurring within lymph nodes draining the subcutaneous site of acute infection with maedi-visna virus (MVV) were studied, and the appearance of infected cells correlated with the immune response. Cells infected with virus were detected in the node by cocultivation from day 4 postinfection (p.i.), with maximum numbers being seen between days 7 and 14, but even then infected cell...

Objectives: The decontamination or physical removal of contaminants from personal protective equipment upon exit from high containment laboratories is crucial to maintain containment and safety of laboratory workers. The current methodology for exiting from high-containment level 4 (CL-4) laboratory calls for laboratory personnel to decontaminate their worn positive pressure suits via “mechanic...

During 2009-10, real time RT-PCR and conventional RT-PCR techniques Used for detecting BTVs RNA in 310 blood samples. For real time and gel based RT-PCR segment-1 and segment-10 selected as conserve genes to search any BTV strains. Using these methods, 58 (%18.7) and 14 (%4.5) positive samples were detected among the clinically suspected sheep. Sensitivity of both molecular techniques evalua...

During 2010-2011, Real-time PCR procedure was used to detecting FMDV RNA on 147 epithelium samples from the field. In this survey, for Real-time PCR from 3D gene segment as conserve region selected for tracking all of seven serotypes FMDV. The assay detected the viral RNA in all serotypes of FMDV. The rRT-PCR specifically detected FMD virus in sample with greater sensitivity than our convention...

  Background :Wide distribution and low half-life of acyclovir has led to a high dose consumption of the drug. Recent studies have shown that encapsulation of acyclovir in nano-carriers can increase effectiveness and decrease its side effects. We investigated the inhibitory effect of acyclovir loaded nano-niosomes against herpes simplex virus type-1 (HSV-1) in cell culture.   Methods : In-vitro...

The ongoing coronavirus pandemic requires more effective disinfection methods. Disinfection using ultraviolet light (UV), especially longer UVC wavelengths, such as 254 and 270/280 nm, has been proven to have virucidal properties, but its adverse effects on human skin eyes limit use enclosed, unoccupied spaces. Several studies shown the effectiveness of blue (405 nm) against bacteria fungi, pro...

Canine distemper virus (CDV) infections cause high morbidity and mortality in dogs. Changes the molecular biological characteristics of Korean CDV strain over multiple cell passages have not been reported. We investigated genetic CD1901-100 for use as an inactivated vaccine strain. Vero cells expressing dog nectin-4 gene (Vero/dNectin-4 cells) were used to adapt CD1901, which was passaged 100 t...

The coronavirus disease 2019 (COVID-19) has become a serious problem for public health since it was identified in the province of Wuhan (China) and spread around world producing high mortality rates economic losses. Nowadays, WHO recognizes traditional, complementary, alternative medicine treating COVID-19 symptoms. Therefore, we investigated antiviral potential hydroalcoholic extract Uncaria t...