OBJECTIVE To determine whether the cognitive function contribution to straight- and curved-path walking differs for older adults. DESIGN Cross-sectional observational study. SETTING Ambulatory clinical research training center. PARTICIPANTS People (N=106) aged 65 to 92 years, able to walk household distances independently with or without an assistive device, and who scored 24 or greater o...

Death is source of mystery, fascination and fear and the deny of death is at the basis of the human motivation [1]. Terror Management Theory [2] suggests that death awareness and the fundamental instinct of self-preservation create a potential for anxiety that individuals try to buffer by using different mechanisms oriented toward meaning and self-esteem striving. While existing research provid...

OBJECTIVE The main goal of the study is to determine the normative values of Trail Making Test (TMT) for people between 20-49 years of age; to examine the effect of age, education and sex variables over TMT scores and identify the reliability coefficient of the test. METHOD The sample of the study consisted of 133 women and 130 men, 261 voluntary and healthy participants in total. The data of...

BACKGROUND Luminal anionic sulphide may contribute to epithelial damage in ulcerative colitis. Thiol methyltransferase (TMT) governs sulphide detoxification by the colonic mucosa and circulating erythrocytes. AIMS To measure levels of TMT activity in erythrocytes of surgically treated cases of colitis or in rectal biopsies of defined groups of colitis. PATIENTS Venepuncture blood was obtain...

BACKGROUND/AIMS The Trail Making Test (TMT) has long been used to investigate deficits in cognitive processing speed and executive function in humans. However, there are few studies that elucidate the neural substrates of the TMT. The aim of the present study was to identify the regional perfusion patterns of the brain associated with performance on the TMT part A (TMT-A) in patients with Alzhe...

In the present study, we determined the effects of a γ-tocopherol-rich mixture of tocopherols (γ-TmT) on the growth and apoptosis of cultured human prostate cancer LNCaP cells. We also determined the effects of dietary γ-TmT on the formation and growth of LNCaP tumors in immunodeficient mice. In the in vitro study, we found that the activity of γ-TmT was stronger than α-tocopherol for inhibitin...

Background The Trail Making Test (TMT) via part B (TMT-B) has been widely used in the evaluation of the executive functions [1]. Apart from the direct scores (time to complete part A and B), derived TMT scores (B-A, B/A, B-A/A) are more and more used, as sensitive measures of prefrontal functioning [2-4]. The aim of the present study was to provide reference data from a large sample of Greek he...

Terror management theory posits that individuals respond positively to people and ideas that bolster their cultural worldviews and negatively to those that threaten their cultural anxiety buffers (Rosenblatt, Greenberg, Solomon, Pyszczynski & Lyon, 1989). Repeated studies have shown that people exposed to awareness of immanent death write different kinds and varying lengths of story narratives ...

Trimethyltin (TMT) is known as a potent neurotoxicant that causes neuronal cell death and neuroinflammation, particularly in the hippocampus. Microglial activation is one of the prominent pathological features of TMT neurotoxicity. Nevertheless, it remains unclear how microglial activation occurs in TMT intoxication. In this study, we aimed to investigate the signaling pathways in TMT-induced m...

Although radical cystectomy (RC) is considered as the standard therapy for muscle-invasive bladder cancer (MIBC), trimodal therapy (TMT) combining transurethral resection of the tumor with radiotherapy and chemotherapy is increasingly recommended as an alternative approach for bladder preservation. In the absence of randomized trials, we compared the clinical outcomes between RC and TMT using p...