Adjuvant-induced arthritis, an autoimmune disease similar to rheumatoid arthritis, was used to investigate possible mechanisms of immune system modulation of the reproductive system. This laboratory previously reported that arthritic male rats have reduced serum testosterone and elevated serum LH concentrations. In the experiments described here, serum prolactin levels were not significantly di...

Despite its infrequent occurrence, testicular schistosomiasis forming pseudo-tumors can be considered in the differential diagnosis of testicular tumors, especially in areas where the parasitic disease is endemic. In this report, we present a case of testicular schistosomiasis caused by Schistosoma mansoni and mimicking a testicular neoplasm. We describe the patterns of a testicular nodule on u...

This case is the first report of a bacteriologically proven testicular abscess in a child caused by Salmonella paratyphi 'A' in Pakistan that clinically simulates a testicular tumour. The case also emphasises that a course of 2 weeks antibiotic is sufficient for testicular abscess if complete surgical debridement is done.

Tuberculosis is a major cause of morbidity and a persisting public health problem in the developing countries. Testicular tuberculosis particularly in isolated form is extremely rare. We report an unique case of testicular tuberculosis in a 20year old male patient who presented in a painless right testicular swelling and whose clinical, radiological and biochemical parameters indicated a germ c...

the testicular torsion which is typically seen in prepuberty is very rare in the early neonatal period; prenatal diagnosis is difficult. herein, we report a five day-old male neonate with swelling and erythema of the right scrotum.  following doppler ultrasound suggestive of testicular torsion, surgical exploration was undertaken. there was gangrene of the right testis with discoloration and ne...

Alternative pre-mRNA splicing (AS) is a key molecular event that allows for protein diversity and plays important roles in development and disease. AS regulations during spermatogenesis and AS aetiology in testicular tumorigenesis have not yet to be characterized. By genome-wide analysis, here we describe alternative splicing features that distinguish distinctive patterns of AS among human test...

Hormone-sensitive lipase (HSL, Lipe, E.C.3.1.1.3) is a multifunctional fatty acyl esterase that is essential for male fertility and spermatogenesis and that also plays important roles in the function of adipocytes, pancreatic beta-cells, and adrenal cortical cells. Gene-targeted HSL-deficient (HSL-/-) male mice are infertile, have a 2-fold reduction in testicular mass, a 2-fold elevation of the...

UNLABELLED We investigated whether or not surgical strategy has an impact on the risk of invasive testicular neoplasia in cases of cryptorchidism. We made a database study of the incidence of testicular neoplasia at surgery for cryptorchidism in childhood, and evaluated if such abnormalities were found in special categories of patients, and also of the incidence of testicular neoplasia after or...

OBJECTIVE The purpose of this study was to assess the role of MRI in the preoperative characterization and local staging of testicular neoplasms. SUBJECTS AND METHODS MRI was performed on 33 patients referred because a testicular mass had been detected clinically and sonographically. Both T1- and T2-weighted sequences were performed with a 1.5-T MRI unit. Gadolinium chelate was administered I...

Testicular fine needle aspiration cytology (FNAC) is widely being used in humans to evaluate the functional testicular mechanism, but its application is very limited in animals especially breeding bulls. This preliminary study was conducted to assess the effect of testicular fine needle aspiration (FNA) technique on testicular biometry and seminal characteristics in Karan Fries crossbred bulls....