background: in radiation therapy, peripheral dose or the dose outside the radiotherapy field, is important when anatomical structures with very low dose tolerances are involved. one of these critical organs in pelvic irradiation is testis. the amount of radiation delivered to the testes in radiotherapy must be kept as small as possible, consistent with the limit dose of this organ. the threshol...

ischemia-reperfusion injury is a possible cause of testicular damage and infertility after testicular torsion and detorsion. the purpose of this study was to evaluate the effect of ghrelin on testicular ischemia-reperfusion damage. a total of 30 adult male rats were selected for the study and divided randomly into 3 groups, each containing 10 rats. animals in the testicular torsion and ghrelin ...

Mechanisms of testicular thermoregulation, the relationship of scrotal, testicular vascular cone (TVC), and testicular morphology with thermoregulatory capability, and their effects on semen quality and sperm production were studied in 20 Bos indicus, 28 crossbred, and 26 Bos taurus bulls. The ratio of testicular artery length and volume to testicular volume were larger (P<0.05) in B. indicus a...

Background: Between 2% and 5% of malignant germ-cell tumors in men arise at extragonadal sites. Of extragonadal germ cell tumors, testicular carcinoma in situ (CIS) are present in 31-42% of cases, and CIS are reported to have low sensitivity to chemotherapy in spite of the various morphology and to have a high likelihood of developing into testicular tumors. A testicular biopsy may thus be high...

anandamide is an endogenous ligand for cannabinoid receptors and has endothelial protective effect against ischemic preconditioning. the purpose of this study was to investigate the effects of cannabinoids on reperfusion injury due to testicular torsion-detorsion (t/d). a total of 36 adult male sprague-dawley rats were divided into 6 groups. testicular ischemia was achieved by twisting the righ...

Cisplatin (Cp) is one of the most effective chemotherapy antineoplastic drugs. Nevertheless, it causes numerous injurious effects on organs, precisely testes. Ixora coccinea (IC) a well-known medicinal herb and has long history use as tonic to promote health. This study revealed inhibitory hydroethanolic extract IC leaves (HEICL) CP-induced testicular damage in male Wistar rats. Thirty (30) adu...

BACKGROUND Although risk estimates for synchronous and metachronous contralateral testicular cancers vary widely, many clinicians recommend routine biopsy of the contralateral testis for patients diagnosed with unilateral testicular cancer. We evaluated the risk of contralateral testicular cancer and survival in a large population-based cohort of men diagnosed with testicular cancer before age ...