A young man with subacute neuronopathy following tetracycline treatment is described. The symptoms started as a sensory dorsal root affection but by time also involved motor nerves. He developed a severe sensory ataxia with pseudoathetotic movements. Other possible aetiologies were scrutinized and excluded. Tetracycline induced neuronopathy is hitherto not reported in the literature. We propose...

INTRODUCTION................................................................ 542 TETRACYCLINE PROPHYLAXIS................... 543 Simian Tularemia.................. 543 Human Tularemia................... 544 TETRACYCLINE THERAPY................... 545 OTHER ANTIBIOTICS................... 546 SUMMARY.................................................................... 547 LITERATURE CITED............

Early studies of the Bacteroides mobilizable transposon NBU1 established that excision, the first step in NBU1 transfer, requires exposure of the cells to tetracycline. More recently, we found that excision is also associated with growth phase; even after exposure to tetracycline, excision is detectable only after the cells enter late exponential phase. The tetracycline effect is mediated by a ...

Abstrak Diare merupakan kegiatan defekasi (buang air besar) yang biasanya berbentuk 1/2 padat atau cenderung lebih cair berlangsung dari tiga kali sehari dalam waktu singkat, vibrio cholera adalah salah satu penyebabnya, bakteri ini gram negatif koma galibnya masa inkubasi 12-72 jam. Bakteri cholerae menyulut penyakit bakteri. Jenis penelitian laboratorium eksperimental dengan menggunakan arsip...

Resistance to macrolides and tetracyclines is increasing among streptococci and co-occurs as their resistance determinants are carried on the same mobile element. We developed a multiplex PCR to facilitate simultaneous and specific detection of resistance determinants for both macrolides [erm(A), erm(B), and mef(A/E)] and tetracyclines [tet(M), tet(O), tet(K), and tet(L)] in streptococci.

Tetracycline, doxycycline, and minocycline were evaluated for their antibacterial activity against methicillin-susceptible and -resistant isolates of Staphylococcus. At clinically achievable levels both doxycycline and minocycline were more active than tetracycline against methicillin-susceptible organisms. Tetracycline and doxycycline had no activity against methicillin-resistant staphylococci...