In spite of the enormous importance, reactions of cationic electrophiles with silylated enol ethers have adopted in organic synthesis,* kinetic data on such reactions are rare.u Previously we have reported rate constants for the reactions of alkenes, allylelement compounds, and enol ethers toward chloro-, methyl-, and alkoxy-substituted benxhydryl cation& Because of the high nucleophilicity of ...

Labeled long chain acyl-CoA, aldehyde, and alcohol (16:0) were incubated in the peritoneal cavity of mice bearing Ehrlich ascites cells and the distribution of radioactivity in the acyl, alkyl, and alk-1-enyl moieties of various neutral lipid and phospholipid classes was compared. The results suggested the following metabolic relations. 1. Alkyl glyceryl ethers are precursors of alk-l-enyl glyc...

Labeled long chain acyl-CoA, aldehyde, and alcohol (16:0) were incubated in the peritoneal cavity of mice bearing Ehrlich ascites cells and the distribution of radioactivity in the acyl, alkyl, and alk-1-enyl moieties of various neutral lipid and phospholipid classes was compared. The results suggested the following metabolic relations. 1. Alkyl glyceryl ethers are precursors of alk-l-enyl glyc...

A series of adamantane functionalized diaza-lariat ethers 1–6 have been prepared and alkali metal picrate extraction profiles determined. The ability of aza-crown ethers 1–6 to extract the alkali metal picrates was compared with that of diaza-18-crown-6 (7) and N,N '-dibenzodiaza-18-crown-6 (8). Na and K transport across bulk liquid membrane was also measured. The results of alkali metal cation...

MP2/6-311++G(d,p) calculations have been carried out to investigate the conformation, protonation and the hydrogen bonding interactions with water of several halogenated ethers (CH(3)OCH(2)Cl, CH(2)ClOCH(2)Cl, CH(3)OCHCl(2), CHFClOCHF(2)). The optimized geometries, ν(CH) harmonic vibrational frequencies and the SAPT decomposition of the interaction energies are studied. The interaction with one...

" When you can't run anymore, you crawl, and when you can't do that, you find someone to carry you "-Joss Whedon's Firefly ep.12-Till alla er som hjälpt till att bära i List of papers This thesis is based on the following papers, referred to in the text by their roman numerals, I-IV: I Lindqvist D., Dahlgren E., and Asplund L. (2017) Biosynthesis of hydroxylated polybrominated diphenyl ethers a...

In this review, we describe direct and indirect photochemical approaches that have been developed for the preparation of phthalimide- and naphthalimide-based, lariat-type crown ethers. The direct route utilizes a strategy in which nitrogen-linked side chains containing polyethoxy-tethered phthalimides and naphthalimides, possessing terminal α-trialkylsilyl groups, are synthesized utilizing conc...

The aim of this study was to synthesize a series of ethylene glycol (EG) ethers and quinoline hybrids of the antimalarial drug artemisinin and to evaluate their antimalarial activity in vitro against Plasmodium falciparum strains. The ethers were synthesized in a one-step process by coupling ethylene glycol (EG) moieties of various chain lengths to carbon 10 of dihydroartemisinin, while the art...

The lipophilic ̄avonoids in leaf and ̄ower of Tanacetum parthenium and T. vulgaris have been compared. While those of T. parthenium are methyl ethers of the ̄avonols 6-hydroxykaempferol and quercetagetin, the surface ̄avonoids of T. vulgare are methyl ethers of the ̄avones scutellarein and 6-hydroxyluteolin. Apigenin and two ̄avone glucuronides are surprisingly present in glandular trichomes on...