This paper reports the design of a new type of micro-fabricated device allowing the directed axon outgrowth from different neuronal subtypes and their subsequent connections to create live neural networks. Micro-fluidic cell culture systems enable the fluidic isolation of the neuronal cell bodies from their axons. Our novel chamber design enables directed axon outgrowth between different neuron...

We studied exposures to higher daily maximum temperatures and concentrations of air pollutants in Tokyo during the summer months of July and August from 1980 to 1995 and their effects on hospital emergency transports for cardiovascular and respiratory diseases for males and females > 65 years of age. Cardiovascular diseases were angina, cardiac insufficiency, hypertension, and myocardial infarc...

This paper describes electrically-activated fluidic valves that operate based on electrowetting through textiles. The valves are fabricated from electrically conductive, insulated, hydrophobic textiles, but the concept can be extended to other porous materials. When the valve is closed, the liquid cannot pass through the hydrophobic textile. Upon application of a potential (in the range of 100-...

The application of electrical fields within a microfluidic channel enables many forms of manipulation necessary for lab-on-a-chip devices. Patterning electrodes inside the microfluidic channel generally requires multi-step optical lithography. Here, we utilize an ion-implantation process to pattern 3D electrodes within a fluidic channel made of polydimethylsiloxane (PDMS). Electrode structuring...

We present a novel 3D printed multimaterial microfluidic proportional valve. The microfluidic valve is a fundamental primitive that enables the development of programmable, automated devices for controlling fluids in a precise manner. We discuss valve characterization results, as well as exploratory design variations in channel width, membrane thickness, and membrane stiffness. Compared to prev...

This research proposes a substrate-integrated waveguide (SIW) cavity sensor to detect several chemicals using the microwave frequency range. The frequency response of the presented SIW sensor is switched by filling a very small quantity of chemical inside of the fluidic channel, which also causes a difference in the effective permittivity. The fluidic channel on this structure is either empty o...

This paper presents the coupled code system of PROTEUS-NODAL and SAM developed for multiphysics simulation molten salt reactors (MSRs). The coupling was made under MOOSE framework by developing a wrapper master application that controls neutronics thermal-fluidic calculations. verified validated using Molten Salt Fast Reactor (MSFR) benchmark problem available experimental data Experiments (MSR...

The parallel linear transports defined by flat linear connection are axiomatically described. On this basis a number of properties, some of which are new, of these transports and connections are derived.

The (parallel linear) transports in tensor spaces generated by derivations of the tensor algebra along paths are axiomatically described. Certain their properties are investigated. Transports along paths defined by derivations of the tensor algebra over a differentiable manifold are considered.