Amorphous solid dispersion drug delivery systems (ASD DDS) were proved to be efficient for the enhancement of solubility and bioavailability poorly water-soluble drugs. One major keys successful preparation ASD is selection appropriate excipients, mostly polymers, which have a crucial role in improving its physical stability. Even though, excipients should chemically inert, there some evidence ...

The main objective of this search was to prepare novel soluble polyureas with improved thermal stability. Accordingly, a new types of polyureas was prepared through the polycondensation reaction of a prepared diamine containing ether, keto, and naphthyl groups with 4,4’-diphenylmethan diisocyanate (MDI), toluene-2,4-diisocyanate (TDI), and isophorone diisocyanate (IPDI) in N-methyl-2-pyrrol...

A bio-based plasticizer, epoxidized acetylation cardanol, was synthesized from cardanol, which experienced acetylation reaction and epoxidation reaction. Chemical structure of epoxidized acetylation cardanol was characterized by FT-IR and 1H NMR. Plasticized PVC films (PVC-P) were prepared by casting method with 40%wt of epoxidized acetylation cardanol as a plasticizer. Thermal s...

The nanostructured anatase TiO2 with high thermal stability was prepared by polymeric sol-gel method without any additives. The particle size distribution of polymeric titania sol was determined by dynamic light scattering (DLS). Then properties of obtained titania were investigated by TG-DTA, XRD, FESEM and TEM. Also, the decolorization capability of resultant anatase was evaluated using methy...

Cutinase has been ascertained as a biocatalyst for biotechnological and industrial bioprocesses. The Glomerella cingulata cutinase was genetically modified to enhance its enzymatic performance to fulfill industrial requirements. Two sites were selected for mutagenesis with the aim of altering the surface electrostatics as well as removing a potentially deamidation-prone asparagine residue. The ...

In this article, an exact analytical solution for thermal buckling analysis of thin functionallygraded (FG) rectangular plates is presented. Based on the classical plate theory and using the principle ofminimum total potential energy, the stability equations are obtained. Since the material properties in FGmaterials are functions of the coordinates (specially the thickness), the stability equat...

In current work, halogenated sunflower oil was reacted with Na2S3 to produce sunflower oil-based polysulfide polymer. Cloisite 30B as organomodified nanoclay was used in different contents to investigate its effect on the properties of the synthesized polymer. All nanocomposites were prepared via in situ polymerization method in aqueous media. Fourier Transform-InfraRe...

Actin is one of the proteins that rely on chaperonins for proper folding. This paper shows that the thermal unfolding of G-actin, as studied by CD and ultraviolet difference spectrometry, coincides with a loss in DNase I-inhibiting activity of the protein. Thus, the DNase I inhibition assay should be useful for systematic studies of actin unfolding and refolding. Using this assay, we have inves...