نتایج جستجو برای: thermoresistant allergen

تعداد نتایج: 12186  

Journal: :Environmental Health Perspectives 2004
Ulrike Gehring Elizabeth Triche Robert T van Strien Kathleen Belanger Theodore Holford Diane R Gold Thomas Jankun Ping Ren Jean-ellen McSharry William S Beckett Thomas A E Platts-Mills Martin D Chapman Michael B Bracken Brian P Leaderer

We assessed the accuracy of questionnaire reports of cat and dog ownership and presence of cockroaches in predicting measured allergen concentrations in house dust. We collected dust samples in the homes of 932 newborns living in New England. Dust samples were taken from the main living area and the infant's bedding. Allergen content of house dust was measured by enzyme-linked immunosorbent ass...

2013
Jonathan S Boomer Amit D Parulekar Brenda M Patterson Huiqing Yin-Declue Christine M Deppong Seth Crockford Nizar N Jarjour Mario Castro Jonathan M Green

BACKGROUND Atopic asthma is characterized by intermittent exacerbations triggered by exposure to allergen. Exacerbations are characterized by an acute inflammatory reaction in the airways, with recruitment of both innate and adaptive immune cells. These cell populations as well as soluble factors are critical for initiating and controlling the inflammatory processes in allergic asthma. Detailed...

Journal: :JCI insight 2017
Jane Al-Kouba Andrew N Wilkinson Malcolm R Starkey Rajeev Rudraraju Rhiannon B Werder Xiao Liu Soi-Cheng Law Jay C Horvat Jeremy F Brooks Geoffrey R Hill Janet M Davies Simon Phipps Philip M Hansbro Raymond J Steptoe

Memory Th2 cell responses underlie the development and perpetuation of allergic diseases. Because these states result from immune dysregulation, established Th2 cell responses represent a significant challenge for conventional immunotherapies. New approaches that overcome the detrimental effects of immune dysregulation are required. We tested whether memory Th2 cell responses were silenced usin...

Journal: :Clinical and Translational Allergy 2023

Background Atopy varies in people of different ages owing to physical conditions and exposure allergens. We aimed cluster based on atopic severity using K-means analysis identify incidence, severity, as well the association among peripheral eosinophils, IgE sensitisation. Methods Consecutive patients (n = 7654) with allergic symptoms undergoing allergen-specific tests were included from 2013 20...

2017
Gabriella Di Felice Paolo Colombo

Allergen-specific immunotherapy was introduced in clinical settings more than 100 years ago. It remains the only curative approach to treating allergic disorders that ameliorates symptoms, reduces medication costs, and blocks the onset of new sensitizations. Despite this clinical evidence and knowledge of some immunological mechanisms, there remain some open questions regarding the safety and e...

Journal: :Journal of clinical pathology 2004
D Sinclair S A Peters

BACKGROUND Measurement of total serum IgE and allergen specific IgE is often requested to assess possible allergy. As public awareness increases, so do requests for allergy assessment; unless there is a clear "allergen suspect" in the history, several allergen specific IgE requests may be made. This increases the likelihood of detecting borderline increases in allergen specific IgE of uncertain...

Journal: :The Journal of allergy and clinical immunology 2003
Samuel J Arbes Richard D Cohn Ming Yin Michael L Muilenberg Harriet A Burge Warren Friedman Darryl C Zeldin

BACKGROUND Although exposure to house dust mite allergen is a major risk factor for allergic sensitization and asthma, nationwide estimates of dust mite allergen levels in US homes have not been reported. OBJECTIVE The purpose of this study was to estimate the prevalence of dust mite allergen in beds of US homes and to identify predictors of dust mite allergen concentration. METHODS Data we...

2015
Jörg Kleine-Tebbe Thilo Jakob

Allergen molecules (synonyms: single allergens, allergen components) open up new horizons for the targeted allergen-specific diagnostics of immunoglobulin E (IgE) in singleplex determination. The following rationales support the targeted use of allergen molecules and, more importantly, improve test properties: (1) increased test sensitivity ("analytical sensitivity"), particularly when importan...

Journal: :The Journal of allergy and clinical immunology 2015
Jeroen Buters Marje Prank Mikhail Sofiev Gudrun Pusch Roberto Albertini Isabella Annesi-Maesano Celia Antunes Heidrun Behrendt Uwe Berger Rui Brandao Sevcan Celenk Carmen Galan Łukasz Grewling Bogdan Jackowiak Roy Kennedy Auli Rantio-Lehtimäki Gerald Reese Ingrida Sauliene Matt Smith Michel Thibaudon Bernhard Weber Lorenzo Cecchi

BACKGROUND Allergies to grass pollen are the number one cause of outdoor hay fever. The human immune system reacts with symptoms to allergen from pollen. OBJECTIVE We investigated the natural variability in release of the major group 5 allergen from grass pollen across Europe. METHODS Airborne pollen and allergens were simultaneously collected daily with a volumetric spore trap and a high-v...

Journal: :The Journal of allergy and clinical immunology 1999
J W Vaughan J A Woodfolk T A Platts-Mills

BACKGROUND High-quality vacuum cleaners and vacuum cleaner bags are often recommended to allergic patients as a means of reducing indoor allergen exposure. A number of vacuum cleaners on the market today claim to capture 99.9% of particles 0.3 microm or larger entering the vacuum cleaner, and many vacuum cleaner bags are now being sold as microfiltration bags. OBJECTIVE The purpose of this st...

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