The nitrile stretching mode of the thiocyanate moiety is a nearly ideal probe for measuring the local electric field arising from the organized environment of the interior of a protein. Nitriles were introduced into three proteins: ribonuclease S (RNase S), human aldose reductase (hALR2), and the reaction center (RC) of Rhodobacter capsulatus, through a facile synthetic scheme for the transform...

In the performance of routine determinations of serum chloride by the automated method, which depends on halide displacement of mercury from the thiocyanate to allow formation of ferric thiocyanate complex, 4 cases of bromide poisoning were detected. Experimental evidence shows the halide substitution to be an equilibrium, with higher formation constants for the heavier halide ions. As a result...

1-Benzyl-2-(methylthio)-imidazole-5-ketone is obtained in a few simple steps starting from thiocyanate and glycine amide (glycin). Subsequent treatment with diethyl phosphorocyanidate and functional group manipulations gives 1-benzyl-5-chloromethyl-imidazolium chloride. This compound is converted under mild O'Donnell conditions into the corresponding L-histidine derivative. After deprotection L...

Patients with subacute combined degeneration who smoked had significantly lowered plasma thiocyanate levels than control smokers, but plasma thiocyanate levels in non-smoking patients with neurological disease due to vitamin B(12) deficiency were not significantly different from control values. The results provide no support for the hypothesis that chronic cyanide intoxication is responsible fo...

Aqueous extract of Calendula officinalis Linn. leaves and flowers has antioxidant action. The activity was determined using the ferric thiocyanate thiobarbituric acid techniques. aqueous extracts petals greater than that leaves. According to findings this study, C. are a possible source natural antioxidants.

We report a green and efficient method for the synthesis of 8-aryl-6-thioxo-6H-1,9-dioxa-7-aza-cyclopenta[a]naphthalen-3-one from condensation ammonium thiocyanate acid chlorides with 7-...

Thiocyanate Ion, Chloramine-T Kinetics of oxidation of potassium thiocyanate by the oxidant chloramine-T (CAT) in presence of NaOH has been studied at 30 °C. At low substrate concentrations, the approximate rate law is, — d[CAT]/dt = k[CAT][KNCS]/[NaOH]2. At higher substrate concentrations, the rate law simplifies to, —d[CAT]/dt = k[CAT]/[NaOH]. Ionic strength and addition of p-toluene sulphona...

tween steady and oscillatory states, and marked sensitivity to stirring rate. Thiocyanate shows none of these features. A mechanistic explanation of the chlorite-bromide oscillations seems within reach given the reactions's similarity to the chlorite-iodide reaction and the success of numerical simulations' ' , 1 2 of batch behavior in the chlorite-bromide system. In contrast, very little is kn...