Silymarin is the active ingredient of milk thistle. Several studies proved that silymarin has antioxidant, anti-inflammatory and anti-cancer properties. Silymarin is widely used for treatment of hepatic and biliary disorders, renal toxicity and is recently used as adjuvant agent for treatment of cancer.

Because cancer is often treated with combination therapy, unexpected pharmacological effects can occur because of drug–drug interactions. Several drugs are able to cause upregulation or downregulation of drug transporters or cytochrome P450 enzymes, particularly CYP3A4. Induction of CYP3A4 may result in decreased plasma levels and therapeutic efficacy of anticancer drugs. Since the pregnane X r...

Two new species of the genus Mesopsyllus Por, 1960 (Canthocamptidae) are described from the Bohai Sea, eastern China. Mesopsyllus dimorphussp. n. and M. spiniferussp. n. differ from their congeners by the presence of two instead of three outer spines on P2-P3 exp-3. They can be differentiated from each other by (1) number of inner setae on P3-P4 enp-2; (2) anterior margin of antennulary segment...

1. The present study was conducted to examine the effects of organic extracts from milk thistle (Silybum marianum), turmeric (Curcuma longa), reishi mushroom (Ganoderma lucidum), and shiitake mushroom (Lentinus edodes) on innate immunity and tumor cell viability. 2. Innate immunity was measured by lymphocyte proliferation and nitric oxide production by macrophages, and the inhibitory effect on ...

ethanol extracts of donkey thistle (Onopordum acanthium L.) was conducted. The were added to the pure distillate from grapes Melnik-55 grapevine variety in amounts 20, 50, 80, 100, 200, 400 and 600 ml. remaining amount liter a distillate. A (without extracts) used as control. addition 50% extract Onopordum L. increased total volatile composition variants 1000:20 1000:50, comparison control samp...

Early growth water stress reduces the extract and fresh oil of Silybum marianum L. (S. marianum) shoots. Two experiments were conducted to reduce effects early drought. Treatments in first experiment organic seed cover fillers at three levels (control, vermicompost, peat moss), hydrogel seven 2, 4, 6 g hydrogelF1 per kg OSC, hydrogelA200 cover), deficit (100, 50, 25% field capacity), second exp...

This study identified the most effective methods for protecting sunflowers from weeds through treatment of crops with herbicides Euro Lightning, Lightning Plus and Express. These options provided substantial protection such as cursed thistle, field bindweed, yellow bristle grass, mustard, frost blite redroot pigweed. In fight against ragweed, excellent action herbicide Express good results. Var...